Tomas Ana, Paut Kusturica Milica, Tomić Zdenko, Horvat Olga, Djurović Koprivica Daniela, Bukumirić Dragica, Sabo Ana
Department of Pharmacology Toxicology and Clinical Pharmacology, Faculty of Medicine Novi Sad, University of Novi Sad, Novi Sad, Serbia.
Department of Dentistry, Faculty of Medicine Novi Sad, University of Novi Sad, Novi Sad, Serbia.
Int J Clin Pharm. 2017 Jun;39(3):507-513. doi: 10.1007/s11096-017-0461-3. Epub 2017 Apr 8.
Background Irregular antibiotic use, including self-medication contributes to the development of antibiotic resistance. One method of accessing antibiotic use in the community is through obtaining an in house inventory of drugs. Objective The aim of this study was to investigate the extent of storage and self-medication with antibiotics agents in households in Novi Sad, Serbia. Setting Households in Novi Sad. Method The study was performed during a 4-month period (October 2015-January 2016) using a sample of 112 households in Novi Sad, Serbia. Two trained interviewers performed the survey by visiting each household. The study consisted of making an inventory of all drugs in household and a semi-structured interview about drug use practices and perceptions. Main outcome measure Number of antibiotics obtained without prescription. Results Out of 112 surveyed households, antibiotics were encountered in 55 (49.1%). Antibiotics constituted 11.98% (92/768) of total number of drug items in households. Out of all antibiotics in households, 41 (44.57%) were not in current use, and presented left-overs from previous treatment. Antibiotics were usually acquired with prescription (67, 67.7%), while about a quarter of packages were used for self-medication-purchased at pharmacy without prescription (19, 20.65%) or obtained through friends or family member (6, 6.52%).The most commonly used antibiotics for self-medication was amoxicillin (reported indications included common cold, cough, pharyngitis and tooth-ache). Conclusion Antibiotics were present in large share of households in Novi Sad. Self-medication with antibiotics and sale of antibiotics without prescription represent an important problem in Serbia.
背景 不规范使用抗生素,包括自我药疗,会导致抗生素耐药性的产生。了解社区抗生素使用情况的一种方法是获取家庭内部的药品清单。目的 本研究旨在调查塞尔维亚诺维萨德市家庭中抗生素制剂的储存和自我药疗情况。地点 诺维萨德市的家庭。方法 本研究于2015年10月至2016年1月的4个月期间进行,采用了塞尔维亚诺维萨德市112户家庭的样本。两名经过培训的访谈员通过走访每户家庭进行调查。该研究包括对家庭中所有药品进行清点以及就用药习惯和认知进行半结构化访谈。主要观察指标 无处方获取的抗生素数量。结果 在112户接受调查的家庭中,55户(49.1%)有抗生素。抗生素占家庭药品总数的11.98%(92/768)。在家庭中所有的抗生素中,41种(44.57%)目前未使用,是以前治疗剩下的。抗生素通常是凭处方获得的(67种,67.7%),而约四分之一的包装用于自我药疗——在药店无处方购买(19种,20.65%)或通过朋友或家庭成员获得(6种,6.52%)。自我药疗最常用的抗生素是阿莫西林(报告的适应证包括普通感冒、咳嗽、咽炎和牙痛)。结论 诺维萨德市大部分家庭都有抗生素。抗生素自我药疗和无处方销售抗生素在塞尔维亚是一个重要问题。