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益康唑对耐多药结核分枝杆菌的抗分枝杆菌活性。

Antimycobacterial activity of econazole against multidrug-resistant strains of Mycobacterium tuberculosis.

作者信息

Ahmad Zahoor, Sharma Sadhna, Khuller G K, Singh Pushpendra, Faujdar Jaya, Katoch V M

机构信息

Department of Biochemistry, Postgraduate Institute of Medical Education & Research, Chandigarh 160 012, India.

出版信息

Int J Antimicrob Agents. 2006 Dec;28(6):543-4. doi: 10.1016/j.ijantimicag.2006.07.028. Epub 2006 Nov 13.

DOI:10.1016/j.ijantimicag.2006.07.028
PMID:17101262
Abstract

This study evaluated the antimycobacterial activity of econazole against multidrug-resistant (MDR) strains of Mycobacterium tuberculosis. The minimum inhibitory concentration (MIC(90)) and minimum bactericidal concentration (MBC(>99.99)) against MDR strains were found to be 0.120-0.125 microg/mL and 0.125-0.150 microg/mL, respectively, demonstrating the antimycobacterial potential of econazole.

摘要

本研究评估了益康唑对耐多药结核分枝杆菌菌株的抗分枝杆菌活性。发现益康唑对耐多药菌株的最低抑菌浓度（MIC(90)）和最低杀菌浓度（MBC(>99.99)）分别为0.120 - 0.125微克/毫升和0.125 - 0.150微克/毫升，这表明了益康唑的抗分枝杆菌潜力。

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