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The analysis of underivatized oligosaccharides by matrix-assisted laser desorption mass spectrometry.

作者信息

Mock K K, Davey M, Cottrell J S

机构信息

Finnigan MAT Ltd., Paradise, Hemel Hempstead, Herts, UK.

出版信息

Biochem Biophys Res Commun. 1991 Jun 14;177(2):644-51. doi: 10.1016/0006-291x(91)91837-3.

DOI:10.1016/0006-291x(91)91837-3
PMID:1710893
Abstract

Matrix Assisted Laser Desorption Mass Spectrometry is shown to provide a rapid and sensitive technique for the analysis of underivatized oligosaccharides. Typical sample loading is 1 pmol and analysis time is around 5 minutes. Through the use of an internal standard, mass measurements are generally accurate to within 0.5 Da. The technique is particularly useful for the analysis of oligosaccharide mixtures released from glycoproteins.

摘要

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