Birang Reza, Poursamimi Jamshid, Gutknecht Norbert, Lampert Friedrich, Mir Maziar
Periodontology Department, Dental Faculty, Isfahan University of Medical Sciences, Esfahan, Iran.
Lasers Med Sci. 2007 Mar;22(1):21-4. doi: 10.1007/s10103-006-0412-z. Epub 2006 Nov 18.
Dentin hypersensitivity (DH) is one of the most common complications that affect patients after periodontal therapy. So far, many investigators have successfully used different types of laser on DH treatment. The aim of this study was to evaluate the comparative effect of Nd:YAG laser and Er:YAG laser on human teeth desensitization. A group of nine patients with a total of 63 chronic hypersensitive teeth were selected. Each one of them should at least have three hypersensitive teeth. These teeth were randomly allocated into three groups. Group 1, Nd:YAG laser (1 W, 15 Hz, 60 s, two times); group 2, Er:YAG laser (100 mJ, 3 Hz, 60 s, two times); and group 3 serves as control group without any treatment. Assessment of pain was performed by a visual analysing scale (VAS) after stimulation of sensitive tooth by using the sharp tip of an explorer. This test was performed before treatment, immediately after that and at 1-, 3- and 6-month intervals after treatment by one blinded examiner. Analysis of VAS score between the three groups at the time of treatment did not show any significant difference (p = 0.506). However, by using repeated-measurement analysis of variance test, significant differences were seen in the three groups between before-treatment VAS score and after treatment (p < 0.0005). This statistically significant difference in the control group demonstrated a placebo effect. However, the effect of using Nd:YAG and Er:YAG lasers was stronger than this placebo effect, so that after removing the effect of the placebo, differences immediately after, 1, 3 and 6 months post treatment between all three groups still were statistically highly significant (p < 0.0005). Compared to the Er:YAG laser group, using Nd:YAG laser resulted in a significant reduction of VAS score at each follow-up examination (p < 0.0005). Although using Nd:YAG and Er:YAG laser in desensitization of hypersensitive teeth showed a placebo effect limited to a short time, results of this study demonstrated that both of these lasers have an acceptable therapeutic effect. The observed effects seemed to last for at least 6 months. It was concluded that Nd:YAG laser is more effective than Er:YAG laser in reduction of patients' pain.
牙本质过敏症（DH）是牙周治疗后影响患者的最常见并发症之一。到目前为止，许多研究人员已成功地将不同类型的激光用于DH治疗。本研究的目的是评估钕：钇铝石榴石激光（Nd：YAG激光）和铒：钇铝石榴石激光（Er：YAG激光）对人牙脱敏的比较效果。选取一组9例患者，共有63颗慢性过敏牙。他们每人至少有三颗过敏牙。这些牙齿被随机分为三组。第1组，Nd：YAG激光（1W，15Hz，60秒，两次）；第2组，Er：YAG激光（100mJ，3Hz，60秒，两次）；第3组作为未进行任何治疗的对照组。在使用探针尖锐端刺激敏感牙后，由一名盲法检查者通过视觉分析量表（VAS）进行疼痛评估。该测试在治疗前、治疗后立即以及治疗后1、3和6个月时进行。治疗时三组之间的VAS评分分析未显示任何显著差异（p = 0.506）。然而，通过重复测量方差分析检验，三组治疗前VAS评分与治疗后相比存在显著差异（p < 0.0005）。对照组的这种统计学显著差异表明存在安慰剂效应。然而，使用Nd：YAG激光和Er：YAG激光的效果强于这种安慰剂效应，因此在消除安慰剂效应后，三组在治疗后立即、1、3和6个月时的差异仍然具有高度统计学意义（p < 0.0005）。与Er：YAG激光组相比，使用Nd：YAG激光在每次随访检查时均导致VAS评分显著降低（p < 0.0005）。尽管使用Nd：YAG激光和Er：YAG激光进行过敏牙脱敏显示出仅限于短时间的安慰剂效应，但本研究结果表明这两种激光均具有可接受的治疗效果。观察到的效果似乎持续至少6个月。得出的结论是，Nd：YAG激光在减轻患者疼痛方面比Er：YAG激光更有效。
