隐匿性念珠菌性绒毛膜羊膜炎病例的羊水穿刺结果及新型蛋白质组学分析
Amniocentesis results and novel proteomic analysis in a case of occult candidal chorioamnionitis.
作者信息
Crawford Julie T, Pereira Leonardo, Buckmaster John, Gravett Michael G, Tolosa Jorge E
机构信息
Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR, USA.
出版信息
J Matern Fetal Neonatal Med. 2006 Oct;19(10):667-70. doi: 10.1080/14767050600738289.
We report a case of subclinical Candida albicans chorioamnionitis with mid-trimester cervical dilation diagnosed by amniotic fluid culture and Gram stain. Proteomic analysis of amniotic fluid demonstrated protein biomarkers previously associated only with bacterial intra-amniotic infections. We hypothesize that since amniotic fluid culture of yeast may take days, novel tests such as proteomic profiling may lead to the development of rapid diagnostic tests for fungal intra-amniotic infections.
我们报告了一例通过羊水培养和革兰氏染色诊断为孕中期宫颈扩张合并亚临床白色念珠菌绒毛膜羊膜炎的病例。羊水的蛋白质组学分析显示了先前仅与细菌性羊膜内感染相关的蛋白质生物标志物。我们推测，由于酵母的羊水培养可能需要数天时间，蛋白质组学分析等新型检测方法可能会推动真菌性羊膜内感染快速诊断检测的发展。
Zotero 插件