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本文引用的文献

1
Nonsevere acute otitis media: a clinical trial comparing outcomes of watchful waiting versus immediate antibiotic treatment.非重度急性中耳炎：一项比较观察等待与立即抗生素治疗效果的临床试验。
Pediatrics. 2005 Jun;115(6):1455-65. doi: 10.1542/peds.2004-1665.
2
To treat or not to treat.治疗还是不治疗。
Pediatrics. 2005 Apr;115(4):1087-9. doi: 10.1542/peds.2004-2874.
3
A randomized, multicenter, double blind, double dummy trial of single dose azithromycin versus high dose amoxicillin for treatment of uncomplicated acute otitis media.单剂量阿奇霉素与高剂量阿莫西林治疗非复杂性急性中耳炎的随机、多中心、双盲、双模拟试验
Pediatr Infect Dis J. 2005 Feb;24(2):153-61. doi: 10.1097/01.inf.0000151024.11703.4a.
4
Community-wide vaccination with the heptavalent pneumococcal conjugate significantly alters the microbiology of acute otitis media.七价肺炎球菌结合疫苗的社区范围接种显著改变了急性中耳炎的微生物学状况。
Pediatr Infect Dis J. 2004 Sep;23(9):829-33. doi: 10.1097/01.inf.0000136868.91756.80.
5
Changes in frequency and pathogens causing acute otitis media in 1995-2003.1995 - 2003年急性中耳炎的发病频率及致病病原体变化
Pediatr Infect Dis J. 2004 Sep;23(9):824-8. doi: 10.1097/01.inf.0000136871.51792.19.
6
Population-based impact of pneumococcal conjugate vaccine in young children.基于人群的肺炎球菌结合疫苗对幼儿的影响。
Pediatrics. 2004 Sep;114(3):755-61. doi: 10.1542/peds.2003-0592-F.
7
Developing community-specific recommendations for first-line treatment of acute otitis media: is high-dose amoxicillin necessary?制定针对急性中耳炎一线治疗的社区特定建议：高剂量阿莫西林是否必要？
Pediatrics. 2004 Aug;114(2):342-7. doi: 10.1542/peds.114.2.342.
8
Diagnosis and management of acute otitis media.急性中耳炎的诊断与管理
Pediatrics. 2004 May;113(5):1451-65. doi: 10.1542/peds.113.5.1451.
9
High-dose azithromycin versus high-dose amoxicillin-clavulanate for treatment of children with recurrent or persistent acute otitis media.大剂量阿奇霉素与大剂量阿莫西林-克拉维酸治疗复发性或持续性急性中耳炎患儿的疗效比较
Antimicrob Agents Chemother. 2003 Oct;47(10):3179-86. doi: 10.1128/AAC.47.10.3179-3186.2003.
10
Acute otitis media: more trouble with the evidence.急性中耳炎：证据方面存在更多问题。
Pediatr Infect Dis J. 2003 Feb;22(2):103-4. doi: 10.1097/01.inf.0000050363.97163.d8.

探寻急性中耳炎的圣杯。

Searching for the Holy Grail of acute otitis media.

作者信息

Block S L

机构信息

Kentucky Pediatric Research, Inc, 201 South 5th Street, Bardstown, KY 40004, USA.

出版信息

Arch Dis Child. 2006 Dec;91(12):959-61. doi: 10.1136/adc.2006.097063.

DOI:10.1136/adc.2006.097063
PMID:17119072
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2082997/
Abstract

Use of PCV7 causes a major shift in the microbiology of AOM towards , but the search for the Holy Grail of AOM still remains elusive

摘要

使用7价肺炎球菌结合疫苗（PCV7）导致急性中耳炎（AOM）的微生物群发生重大转变，趋向于……，但寻找AOM的圣杯仍然难以实现