Perera Frederica, Viswanathan Sheila, Whyatt Robin, Tang Deliang, Miller Rachel L, Rauh Virginia
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Ann N Y Acad Sci. 2006 Sep;1076:15-28. doi: 10.1196/annals.1371.018.
A growing body of evidence has been generated indicating that the fetus, infant, and young child are especially susceptible to environmental toxicants as diverse as polycyclic aromatic hydrocarbons (PAHs), pesticides, lead, mercury, polychlorinated biphenyls (PCBs), and environmental tobacco smoke (ETS). Exposures to these toxicants may be related to the increases in recent decades in childhood asthma, cancer, and developmental disability. The Columbia Center for Children's Environmental Health (CCCEH), located in New York City, has developed four cohorts around the world to elucidate the relationships between these exposures and childhood illness. This article summarizes the recent findings from the Center's projects in the context of current research in children's environmental health.
越来越多的证据表明，胎儿、婴儿和幼儿特别容易受到多种环境毒物的影响，如多环芳烃（PAH）、农药、铅、汞、多氯联苯（PCB）和环境烟草烟雾（ETS）。接触这些毒物可能与近几十年来儿童哮喘、癌症和发育障碍发病率的上升有关。位于纽约市的哥伦比亚儿童环境卫生中心（CCCEH）在全球范围内开展了四个队列研究，以阐明这些接触与儿童疾病之间的关系。本文结合当前儿童环境卫生研究，总结了该中心项目的最新发现。
