通过分子方法鉴定出卷枝毛霉是原发性皮肤接合菌病的病因。
Mucor circinelloides was identified by molecular methods as a cause of primary cutaneous zygomycosis.
作者信息
Iwen Peter C, Sigler Lynne, Noel Rhonda K, Freifeld Alison G
机构信息
Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68198-6495, USA.
出版信息
J Clin Microbiol. 2007 Feb;45(2):636-40. doi: 10.1128/JCM.01907-06. Epub 2006 Nov 22.
Abstract
A case of primary cutaneous zygomycosis caused by Mucor circinelloides is described. Histopathology showed typical hyphae along with chlamydospores. The isolate was identified by molecular and phenotypic methods. The utility of sequence analysis of the internal transcribed spacer region is highlighted; however, further studies are needed to assess species genetic heterogeneity.
摘要
描述了1例由卷枝毛霉引起的原发性皮肤接合菌病病例。组织病理学显示典型的菌丝以及厚垣孢子。通过分子和表型方法对分离株进行了鉴定。强调了转录间隔区序列分析的实用性；然而，需要进一步研究来评估物种的遗传异质性。
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