Zhang H M
Department of Pathology, Norman Bethune Medical University.
Zhonghua Bing Li Xue Za Zhi. 1991 Mar;20(1):41-3.
A primary carcinoid tumor of testis was studied. The tumor cells showed a strong positive reaction to argyrophil or argentaffin stainings, and neuroendocrine granules were identified by electron microscopy. Immunohistochemically, tumor cells expressed various markers such as those for NSE, synaptophysin, CG, Leu-7, 5-HT, HCG, cytokeratin, EMA, CEA and PACP, which indicated the special multiple directions of differentiation of cells possessing neuroendocrinal, epithelial or carcinoembryonic behavior.
对一例睾丸原发性类癌肿瘤进行了研究。肿瘤细胞对嗜银或亲银染色呈强阳性反应，通过电子显微镜鉴定出神经内分泌颗粒。免疫组织化学分析显示，肿瘤细胞表达多种标志物，如神经元特异性烯醇化酶（NSE）、突触素、嗜铬粒蛋白（CG）、Leu-7、5-羟色胺（5-HT）、人绒毛膜促性腺激素（HCG）、细胞角蛋白、上皮膜抗原（EMA）、癌胚抗原（CEA）和嗜铬素A（PACP），这表明具有神经内分泌、上皮或癌胚行为的细胞存在特殊的多向分化。
