Brito Luciara L, Barreto Maurício L, Silva Rita De Cássia R, Assis Ana Marlúcia O, Reis Mitermayer G, Parraga Isabel M, Blanton Ronald E
Instituto de Saúde Coletiva, Federal University of Bahia, Salvador, Brazil.
Am J Trop Med Hyg. 2006 Nov;75(5):939-44.
To determine the role of moderate- and low-intensity infections with Schistosoma mansoni and intestinal helminths (hookworm, Trichuris trichiura, Ascaris lumbricoides) on the prevalence of anemia and their relationship to iron consumption, a cross-section of 1,709 children in rural Brazil was studied. All participants were selected for infection with one or multiple helminthic parasites, and demographic, anthropometric, and dietary intake were surveyed. The prevalence and intensity were as follows: hookworm infection, 15.7% and 8.6 eggs/g; T. trichiura, 74.8% and 190.5 eggs/g; A. lumbricoides, 63% and 1,905.5 eggs/g; S. mansoni, 44.5% and 60.3 eggs/g. There was no increase in odds ratio for anemia with any combination of intestinal helminths without S. mansoni infection. By logistic regression, the odds ratio for having anemia when infected with S. mansoni and two intestinal helminths was 1.7 (95% CI, 1.1-2.5) and for S. mansoni and three intestinal helminths was 2.4 (95% CI, 1.2-4.6) compared with children with a single parasite species. Children with an adequate intake of iron had no increased odds of anemia independent of the combination of parasite infections.
为了确定曼氏血吸虫以及肠道蠕虫（钩虫、鞭虫、蛔虫）的中度和低度感染在贫血患病率中的作用及其与铁摄入量的关系，对巴西农村地区的1709名儿童进行了一项横断面研究。所有参与者均被选定为感染了一种或多种蠕虫寄生虫，并对其人口统计学、人体测量学和饮食摄入量进行了调查。感染率和感染强度如下：钩虫感染，15.7%和8.6个虫卵/克；鞭虫，74.8%和190.5个虫卵/克；蛔虫，63%和1905.5个虫卵/克；曼氏血吸虫，44.5%和60.3个虫卵/克。在未感染曼氏血吸虫的情况下，任何肠道蠕虫组合导致贫血的比值比均未增加。通过逻辑回归分析，与感染单一寄生虫种类的儿童相比，感染曼氏血吸虫和两种肠道蠕虫时患贫血的比值比为1.7（95%置信区间，1.1 - 2.5），感染曼氏血吸虫和三种肠道蠕虫时患贫血的比值比为2.4（95%置信区间，1.2 - 4.6）。铁摄入量充足的儿童，无论寄生虫感染组合如何，患贫血的几率均未增加。
