Medical Department, Federal University of São Carlos, Brazil - DMED UFSCAR, Rod. Washington Luiz, km 235, São Carlos, SP13565-905, Brazil.
Nutrition School, University of São Paulo, Brazil - FMRP-USP, Ribeirao Preto, Brazil.
Public Health Nutr. 2021 Dec;24(18):6450-6465. doi: 10.1017/S136898002100286X. Epub 2021 Jul 2.
To estimate the prevalence of anaemia in Brazilian children up to 83·9 months old.
Systematic review and meta-analysis, using databases PubMed, Scopus, SciELO, Lilacs, Google Scholar, Periódicos Capes, Arca, Biblioteca Virtual em Saúde, Microsoft Academic Search and Cochrane Library using search terms: anaemia, prevalence, child and Brazil. PROSPERO Registration number: CRD42020208818.
Cross-sectional, cohort, case-control and intervention studies published between 2007 and 2020 were searched, excluding those who assessed children with an illness or chronic condition. The main outcome was anaemia prevalence. Random effects models based on the inverse variance method were used to estimate pooled prevalence measures. Sensitivity analyses removed studies with high contribution to overall heterogeneity.
From 6790 first screened, 134 eligible studies were included, totalling 46 978 children aged zero to 83·9 months analysed, with adequate regions representativeness.
Pooled prevalence of anaemia was 33 % (95 % CI 30, 35). Sensitivity analyses showed that withdrawal of studies that contributed to high heterogeneity did not influence national average prevalence.
Childhood anaemia is still a serious public health problem in Brazil, exposing 33 % of Brazilian children to the anaemia repercussions. The main limitation of the study is the estimation of national prevalence based on local surveys, but a large number of studies were included, with representation in all regions of the country, giving strength to the results. In Brazil, more public policies are needed to promote supplementation, fortification and access to healthy eating to reduce the high level of anaemia among children.
估计巴西 0-83.9 月龄儿童贫血的患病率。
系统评价和荟萃分析,使用 PubMed、Scopus、SciELO、Lilacs、Google Scholar、Capes 期刊、Arca、巴西虚拟健康图书馆、Microsoft Academic Search 和 Cochrane Library 数据库,检索词为:贫血、患病率、儿童和巴西。PROSPERO 注册号:CRD42020208818。
本研究纳入了 2007 年至 2020 年间发表的横断面、队列、病例对照和干预研究,排除了评估患有疾病或慢性病儿童的研究。主要结局指标为贫血患病率。采用基于逆方差法的随机效应模型估计汇总患病率。敏感性分析去除了对总体异质性有较大贡献的研究。
从 6790 篇初次筛选的文献中,有 134 篇符合条件的研究被纳入,共纳入了 46978 名 0-83.9 月龄儿童进行分析,这些研究具有较好的地区代表性。
贫血患病率的汇总值为 33%(95%CI 30, 35)。敏感性分析显示,去除对总体异质性贡献较大的研究并不影响全国平均患病率。
巴西儿童贫血仍是一个严重的公共卫生问题,33%的巴西儿童受到贫血的影响。本研究的主要局限性是根据当地调查估计全国患病率,但纳入了大量研究,覆盖了该国所有地区,为结果提供了有力支持。在巴西,需要制定更多的公共政策来促进补充、强化和获得健康饮食,以降低儿童贫血的高发生率。