Blouin L T, Marcus F I, Lampe L
Department of Internal Medicine, University of Arizona Health Sciences Center, Tucson.
Pacing Clin Electrophysiol. 1991 May;14(5 Pt 1):807-13. doi: 10.1111/j.1540-8159.1991.tb04111.x.
Accurate measurement of temperature at the interface of the delivery electrode and the tissue during transcatheter delivery of radiofrequency energy (RFE) for ablation would provide better control of lesion production. Electromagnetic energy fields can affect the accuracy of temperature measurement with thermistors. An electrode probe was fabricated with a thermistor and an optical sensor in the center of the delivery electrode. Simultaneous temperature measurements during RFE delivery to cardiac tissue in the 37 degrees C bath showed good agreement between the sensors, indicating that the RFE field did not cause errors in thermistor temperature measurements with the electrode probe used. A second electrode probe was designed to determine optimal thermistor location. It was constructed using two thermistors with identical temperature-resistance curves. One thermistor protruded through a hole in the side of the delivery electrode and was thermally isolated from it. The other thermistor was bonded to the inner surface of the electrode with heat conductive epoxy. The electrode was placed in contact with cardiac tissue in a 37 degrees C bath of flowing saline with the protruding thermistor centered in the area to be heated. Temperatures measured at steady state during RFE delivery with the protruding thermistor were consistently higher than those of the inner wall thermistor, ranging from 1.8 degrees C difference at 46 degrees C to 8.3 degrees C difference at 75 degrees C interface temperature. The thermistor must be in contact with the tissue and thermally isolated from the delivery electrode for accurate determination of electrode/tissue interface temperature.
在经导管输送射频能量（RFE）进行消融过程中，准确测量输送电极与组织界面处的温度将能更好地控制损伤的产生。电磁能量场会影响热敏电阻温度测量的准确性。制作了一种电极探头，在输送电极的中心放置了一个热敏电阻和一个光学传感器。在37摄氏度水浴中对心脏组织进行RFE输送期间的同步温度测量显示，传感器之间具有良好的一致性，这表明使用的电极探头在RFE场中进行热敏电阻温度测量时不会产生误差。设计了第二个电极探头以确定热敏电阻的最佳位置。它由两个具有相同温度 - 电阻曲线的热敏电阻构成。一个热敏电阻穿过输送电极侧面的一个孔伸出，并与电极热隔离。另一个热敏电阻用导热环氧树脂粘结到电极的内表面。将电极放置在37摄氏度流动盐水浴中与心脏组织接触，使伸出的热敏电阻位于待加热区域的中心。在RFE输送期间，伸出的热敏电阻在稳态下测量的温度始终高于内壁热敏电阻的温度，在46摄氏度时温差为1.8摄氏度，在75摄氏度界面温度时温差为8.3摄氏度。为了准确测定电极/组织界面温度，热敏电阻必须与组织接触并与输送电极热隔离。
