Rezza G, Valdarchi C, Puzelli S, Ciotti M, Farchi F, Fabiani C, Calzoletti L, Donatelli I, Perno C F
Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy.
Euro Surveill. 2006;11(10):251-3.
Limited information is available on the viral aetiology of influenza-like illness (ILI) in Southern European countries. Hereby we report the main findings of a survey conducted in the area of Rome during the 2004-2005 winter season.ILI cases were defined as individuals with fever >37.5 degrees C and at least one constitutional symptom and one respiratory symptom, recruited during the survey period. Influenza and other respiratory viruses were identified using polymerase chain reaction (PCR) on throat swabs. Basic individual information was collected through a standard form. Of 173 ILI cases enrolled, 74 tested positive for one virus, and two tested positive for two viruses. Overall, 33.5% of the cases were positive for influenza viruses, 5.2% for adenoviruses, 3.5% for parainfluenza viruses, 1.7% for coronaviruses, and 1.2% for the respiratory syncitial virus. The proportion of influenza virus detection was higher in the 'high influenza activity' period. The distribution of viral agents varied across age groups, influenza viruses being more likely to be detected in younger patients. Viral pathogens were identified in less than 50% of ILI cases occurred during a high activity influenza season. The detection of other than influenza viruses was sporadic, without evidence of large outbreaks due to specific agents.
关于南欧国家流感样疾病（ILI）的病毒病因，可用信息有限。在此，我们报告2004 - 2005年冬季在罗马地区进行的一项调查的主要结果。ILI病例定义为在调查期间招募的体温高于37.5摄氏度且至少有一个全身症状和一个呼吸道症状的个体。通过对咽拭子进行聚合酶链反应（PCR）来鉴定流感病毒和其他呼吸道病毒。通过标准表格收集基本个人信息。在纳入的173例ILI病例中，74例一种病毒检测呈阳性，2例两种病毒检测呈阳性。总体而言，33.5%的病例流感病毒检测呈阳性，5.2%为腺病毒，3.5%为副流感病毒，1.7%为冠状病毒，1.2%为呼吸道合胞病毒。在“高流感活动”期，流感病毒检测比例更高。病毒病原体的分布因年龄组而异，流感病毒在年轻患者中更易被检测到。在流感高活动季节发生的ILI病例中，不到50%的病例鉴定出病毒病原体。除流感病毒外的其他病毒检测呈散发性，没有证据表明有特定病原体导致的大规模暴发。
