Liu Dong-Ze, Wang Fei, Liao Tou-Gen, Tang Jian-Guo, Steglich Wolfgang, Zhu Hua-Jie, Liu Ji-Kai
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P.R. China.
Org Lett. 2006 Dec 7;8(25):5749-52. doi: 10.1021/ol062307u.
The structure and absolute configuration of vibralactone (1) from the cultures of the Basidiomycete Boreostereum vibrans were established by spectroscopic methods and computational methods. Vibralactone, an unusual fused beta-lactone-type metabolite, was found to inhibit pancreatic lipase with an IC50 of 0.4 microg/mL. [structure: see text]
通过光谱方法和计算方法确定了担子菌 Vibrans 培养物中振动内酯（1）的结构和绝对构型。振动内酯是一种不寻常的稠合β-内酯型代谢产物，发现它能抑制胰腺脂肪酶，IC50 为 0.4 微克/毫升。[结构：见正文]
