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产前抑郁对胎儿及新生儿的影响:综述

Prenatal depression effects on the fetus and newborn: a review.

作者信息

Field Tiffany, Diego Miguel, Hernandez-Reif Maria

机构信息

Touch Research Institutes, University of Miami, School of Medicine, P.O. Box 016820, Miami, Florida, 33101, United States.

出版信息

Infant Behav Dev. 2006 Jul;29(3):445-55. doi: 10.1016/j.infbeh.2006.03.003. Epub 2006 May 30.

DOI:10.1016/j.infbeh.2006.03.003
PMID:17138297
Abstract

A review of research on prenatal depression effects on the fetus and newborn suggests that they experience prenatal, perinatal and postnatal complications. Fetal activity is elevated, prenatal growth is delayed, and prematurity and low birthweight occur more often. Newborns of depressed mothers then show a biochemical/physiological profile that mimics their mothers' prenatal biochemical/physiological profile including elevated cortisol, lower levels of dopamine and serotonin, greater relative right frontal EEG activation and lower vagal tone. Elevated prenatal maternal cortisol is the strongest predictor of these neonatal outcomes. Moderate pressure massage can alleviate these effects including reducing prematurity.

摘要

一项关于产前抑郁症对胎儿和新生儿影响的研究综述表明,他们会经历产前、围产期和产后并发症。胎儿活动增加,产前生长延迟,早产和低体重出生更为常见。抑郁母亲的新生儿随后表现出一种生化/生理特征,类似于其母亲的产前生化/生理特征,包括皮质醇升高、多巴胺和血清素水平降低、右额叶脑电图相对激活增加和迷走神经张力降低。产前母亲皮质醇升高是这些新生儿结局的最强预测因素。适度的压力按摩可以减轻这些影响,包括减少早产。

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