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罗伊氏乳杆菌对含亚碲酸盐培养基上金黄色葡萄球菌生长的抑制作用取决于CyuC和硫醇的产生。

Inhibition of Staphylococcus aureus growth on tellurite-containing media by Lactobacillus reuteri Is dependent on CyuC and thiol production.

作者信息

Turner Mark S, Lo Raquel, Giffard Philip M

机构信息

Infectious Diseases Program, Cells and Tissue Domain, Institute for Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia.

出版信息

Appl Environ Microbiol. 2007 Feb;73(3):1005-9. doi: 10.1128/AEM.02100-06. Epub 2006 Dec 1.

Abstract

Lactobacillus reuteri inhibits Staphylococcus aureus growth on Baird-Parker agar. This activity required the presence of tellurite and was not shared with other lactic acid bacteria or an L. reuteri mutant defective in cystine metabolism. Secreted products generated from L. reuteri cystine metabolism and thiols were shown to augment tellurite toxicity.

摘要

罗伊氏乳杆菌可抑制金黄色葡萄球菌在贝尔德-帕克琼脂上的生长。该活性需要亚碲酸盐的存在,且其他乳酸菌或在胱氨酸代谢方面存在缺陷的罗伊氏乳杆菌突变体均不具备此活性。研究表明,罗伊氏乳杆菌胱氨酸代谢产生的分泌产物和硫醇可增强亚碲酸盐的毒性。

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