Niedermaier G, Wollanke B, Hoffmann R, Brem S, Gerhards H
Klinik für Pferde der Ludwig-Maximilians-Universität München.
Dtsch Tierarztl Wochenschr. 2006 Nov;113(11):418-22.
Equine recurrent uveitis (ERU) is caused by persistent intraocular leptospira, which appear to use the vitreous body as a refuge. The detection of leptospira in the vitreous body of horses with spontaneous ERU by histological methods has not yet been described. Thirty eight vitreous body samples from 36 horses with ERU (collected during vitrectomy), and 10 vitreous body samples obtained from 5 horses without ocular disease (control group) were examined by transmission electron microscopy. Prior to sample collection, 2 ml of a leptospira culture suspension were injected into the vitreous body of 2 eyes enucleated from horses of the control group. The detection of leptospira in samples, experimentally inoculated with these bacteria was uncomplicated; in vitreous body samples from horses with spontaneous ERU the detection was successful in only a few cases (3/38). The morphologically varying envelope of leptospira in vitreous body samples of horses which developed ERU spontaneously suggests the existence of a bacterial masquerade in vivo.
马复发性葡萄膜炎（ERU）由眼内持续存在的钩端螺旋体引起，这些钩端螺旋体似乎将玻璃体作为避难所。尚未见通过组织学方法在患有自发性ERU的马的玻璃体内检测到钩端螺旋体的报道。对36匹患有ERU的马（在玻璃体切割术中采集）的38份玻璃体样本以及从5匹无眼部疾病的马（对照组）获得的10份玻璃体样本进行了透射电子显微镜检查。在样本采集前，将2 ml钩端螺旋体培养悬液注入从对照组马摘除的2只眼睛的玻璃体内。在实验接种这些细菌的样本中检测钩端螺旋体并不复杂；在患有自发性ERU的马的玻璃体样本中，仅在少数病例（3/38）中成功检测到。自发发生ERU的马的玻璃体样本中形态各异的钩端螺旋体包膜表明体内存在细菌伪装现象。
