参加药物治疗试验的可卡因和大麻依赖者的特征。
Characteristics of cocaine- and marijuana-dependent subjects presenting for medication treatment trials.
作者信息
McRae Aimee L, Hedden Sarra L, Malcolm Robert J, Carter Rickey E, Brady Kathleen T
机构信息
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, USA.
出版信息
Addict Behav. 2007 Jul;32(7):1433-40. doi: 10.1016/j.addbeh.2006.10.007. Epub 2006 Dec 5.
Abstract
Evaluation of the characteristics of individuals presenting for substance abuse treatment can provide important information to help focus treatment services. In this study, demographic and clinical characteristics of individuals presenting for medication trials for the treatment of cocaine or marijuana dependence were compared. Marijuana-dependent subjects were generally younger than cocaine-dependent subjects, more likely to be Caucasian, and completed more years of education. Marijuana-dependent subjects also reported significantly more days using than cocaine-dependent subjects, as well as higher levels of craving. Some differences in psychiatric symptomatology were also noted, with cocaine-dependent subjects more likely to report anxiety symptoms and marijuana-dependent subjects reporting more past depressive episodes. Past and current other drug use was similar between the two groups. These results highlight the significant impairments associated with marijuana and cocaine dependence.
摘要
对寻求药物滥用治疗的个体特征进行评估可为聚焦治疗服务提供重要信息。在本研究中，对寻求治疗可卡因或大麻依赖的药物试验的个体的人口统计学和临床特征进行了比较。大麻依赖者通常比可卡因依赖者年轻，更可能是白种人，且受教育年限更长。大麻依赖者报告的使用天数也显著多于可卡因依赖者，且渴望程度更高。还注意到精神症状学方面的一些差异，可卡因依赖者更可能报告焦虑症状，而大麻依赖者报告有更多过去的抑郁发作。两组之间过去和当前的其他药物使用情况相似。这些结果凸显了与大麻和可卡因依赖相关的显著损害。
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