Suppr超能文献

法国艾滋病病毒感染者对非职业性艾滋病病毒暴露后预防的认知:需要更精准的目标定位。

Awareness of non-occupational HIV postexposure prophylaxis among French people living with HIV: the need for better targeting.

作者信息

Rey Dominique, Bouhnik Anne-Déborah, Peretti-Watel Patrick, Obadia Yolande, Spire Bruno

机构信息

South-Eastern Health Regional Observatory (ORS PACA), Marseille, France.

出版信息

AIDS. 2007 Jan;21 Suppl 1:S71-6. doi: 10.1097/01.aids.0000255088.44297.26.

Abstract

BACKGROUND

Since 1998, French HIV prevention guidelines have recommended the use of HIV post-exposure prophylaxis (PEP) after unprotected sex with a HIV-positive partner who should be informed about this option. This study analysed factors associated with PEP awareness in a population of individuals living with HIV/AIDS (PLHAs).

METHODS

In 2003, a face-to-face survey was conducted among PLHAs selected from a random stratified sample of 102 French hospital departments delivering HIV care. Those who knew about PEP and those who did not were compared to identify factors related to PEP awareness in the sub-sample who reported that they had been sexually active in the prior 12 months.

RESULTS

Among the 2,280 sexually active PLHAs, the median age was 40 years. Women comprised 26% of the sample, 41% were homosexual men and 16% were immigrants. Thirty percent of individuals reported not being aware of the availability of PEP. After multiple adjustment, factors associated with lack of PEP awareness were a low educational level, unemployment, older age, and CD4 cell counts<200. In addition, homosexual men showed a higher level of PEP awareness compared with the other participants, especially when compared with immigrant heterosexual men and women. Individuals who reported having unprotected sex with a non-HIV-positive steady partner also independently showed lower levels of PEP awareness. Finally, reporting having casual partners was associated with better awareness.

CONCLUSION

Awareness of PEP is insufficient among PLHAs, especially among immigrants. Programmes aimed at improving positive prevention among PLHAs are much needed and should be promoted.

摘要

背景

自1998年以来,法国的艾滋病预防指南建议,在与HIV阳性伴侣发生无保护性行为后应使用艾滋病暴露后预防(PEP)措施,且应告知该伴侣有此选择。本研究分析了与艾滋病毒/艾滋病感染者(PLHAs)群体中PEP知晓情况相关的因素。

方法

2003年,对从法国102个提供艾滋病护理的医院科室的随机分层样本中选取的PLHAs进行了面对面调查。对知晓PEP的人和不知晓PEP的人进行比较,以确定在报告过去12个月有性活动的子样本中与PEP知晓情况相关的因素。

结果

在2280名有性活动的PLHAs中,年龄中位数为40岁。女性占样本的26%,男同性恋者占41%,移民占16%。30%的人报告不知道有PEP可用。经过多重调整后,与缺乏PEP知晓情况相关的因素包括教育水平低、失业、年龄较大以及CD4细胞计数<200。此外,与其他参与者相比,男同性恋者的PEP知晓水平更高,尤其是与移民异性恋男性和女性相比。报告与非HIV阳性固定伴侣发生无保护性行为的个体也独立显示出较低的PEP知晓水平。最后,报告有临时伴侣与更好的知晓情况相关。

结论

PLHAs中对PEP的知晓情况不足,尤其是在移民中。非常需要旨在改善PLHAs中积极预防措施的项目,并应加以推广。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验