Ségalat Laurent
CNRS-UMR 5534, University of Lyon, Lyon, France
ACS Chem Biol. 2006 Jun 20;1(5):277-8. doi: 10.1021/cb600221m.
Identification of bioactive molecules and their targets impedes the process of drug development. In a recent paper, a genetically tractable organism, the Caenorhabditis elegans worm, is shown to be a viable screening system in which the drug target and the pathway it activates can be readily identified.
生物活性分子及其靶点的鉴定阻碍了药物开发进程。在最近的一篇论文中，一种具有遗传易处理性的生物——秀丽隐杆线虫，被证明是一种可行的筛选系统，在该系统中可以轻松鉴定出药物靶点及其激活的信号通路。
