Baumann Leslie
Department of Dermatology, University of Miami, USA.
J Cosmet Dermatol. 2004 Dec;3(4):249-50. doi: 10.1111/j.1473-2130.2004.00143.x.
The new bioengineered human collagen products and the various hyaluronic acid (HA) fillers are all safe and effective agents for soft tissue augmentation. There is no one best filler for all purposes and optimal results are achieved by using these products in various combinations. In my opinion, HA-containing products provide volume while collagen products are better suited to provide structural support. Less downtime is associated with the collagen products, due to the platelet-aggregating effects of collagen and the eosinophil-stabilizing effects of lidocaine. Using collagen in combination with HA, during the same office visit, may help reduce some of the bruising and swelling seen with HA alone.
新型生物工程人胶原蛋白产品和各种透明质酸（HA）填充剂都是用于软组织填充的安全有效制剂。没有一种填充剂适用于所有目的，通过将这些产品以各种组合使用可获得最佳效果。在我看来，含HA的产品可增加容积，而胶原蛋白产品更适合提供结构支撑。由于胶原蛋白的血小板聚集作用和利多卡因的嗜酸性粒细胞稳定作用，胶原蛋白产品的停工期较短。在同一次门诊就诊时将胶原蛋白与HA联合使用，可能有助于减少单独使用HA时出现的一些瘀伤和肿胀。
