Nikolopoulou Melita, Katsenos Stamatis, Psathakis Kostas, Rallis Efstathios, Sampaziotis Dimitrios, Panagou Panagiotis, Tsintiris Kostas, Bouros Demosthenes
Department of Pneumonology, Army General Hospital of Athens, Athens, Greece.
BMC Pulm Med. 2006 Dec 13;6:26. doi: 10.1186/1471-2466-6-26.
Sarcoidosis is rarely associated with a distinct disease. One disease infrequently associated with sarcoidosis is psoriasis.
This case study describes a 38-year-old male, who presented with chest pain, high-grade fever, arthralgias and a skin rash accompanied by bilateral hilar lymphadenopathy on his chest radiograph. Extensive investigations including fiber-optic bronchoscopy with bronchoalveolar lavage and labial and skin biopsies, demonstrated that two distinct clinical entities co-existed in the same patient: pulmonary sarcoidosis and psoriasis vulgaris. Combination therapy for both diseases was applied and the patient was greatly improved.
This is the first well-documented case of sarcoidosis and psoriasis in the same patient, reported on the basis of safe and widely-used techniques that were not available until fairly recently. These disorders might share common pathogenic mechanisms that could explain their co-existence in the patient.
结节病很少与一种独特的疾病相关联。银屑病是一种很少与结节病相关的疾病。
本病例研究描述了一名38岁男性,他出现胸痛、高热、关节痛和皮疹,胸部X线片显示双侧肺门淋巴结肿大。包括纤维支气管镜检查及支气管肺泡灌洗、唇部和皮肤活检在内的广泛检查表明,同一患者同时存在两种不同的临床病症:肺结节病和寻常型银屑病。对这两种疾病采用了联合治疗,患者病情大为改善。
这是首例有充分记录的同一患者同时患有结节病和银屑病的病例,是基于直到最近才有的安全且广泛应用的技术报告的。这些病症可能共享共同的致病机制,这可以解释它们在该患者身上的共存。