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秘鲁亚马逊地区使用的一些药用树皮的抗菌活性。

Antimicrobial activity of some medicinal barks used in Peruvian Amazon.

作者信息

Kloucek P, Svobodova B, Polesny Z, Langrova I, Smrcek S, Kokoska L

机构信息

Department of Crop Production, Faculty of Agrobiology, Food and Natural Resources, Czech University of Agriculture Prague, Kamycka 129, 165 21 Prague 6-Suchdol, Czech Republic.

出版信息

J Ethnopharmacol. 2007 May 4;111(2):427-9. doi: 10.1016/j.jep.2006.11.010. Epub 2006 Nov 18.

Abstract

The aim of this study was to evaluate the antimicrobial activity of six barks traditionally used in Callería District (Ucayali Department, Peru) for treating conditions likely to be associated with microorganisms. Ethanol extracts of stem barks of Abuta grandifolia (Menispermaceae), Dipteryx micrantha (Leguminosae), Cordia alliodora (Boraginaceae), Naucleopsis glabra (Moraceae), Pterocarpus rohrii (Leguminosae), and root bark of Maytenus macrocarpa (Celastraceae) were tested against nine bacteria and one yeast using the broth microdilution method. All plants possessed significant antimicrobial effect, however, the extract of Naucleopsis glabra exhibited the strongest activity against Gram-positive bacteria (MICs ranging from 62.5 to 125 microg/ml), while the broadest spectrum of action was shown by the extract of Maytenus macrocarpa, which inhibited all the strains tested with MICs ranging from 125 to 250 microg/ml.

摘要

本研究旨在评估秘鲁乌卡亚利省卡列里亚区传统上用于治疗可能与微生物相关病症的六种树皮的抗菌活性。采用肉汤微量稀释法,对大叶阿木通(防己科)、小花双翼豆(豆科)、香肉果(紫草科)、光叶乌口树(桑科)、红果紫檀(豆科)的茎皮乙醇提取物以及大果美登木(卫矛科)的根皮乙醇提取物针对九种细菌和一种酵母菌进行了测试。所有植物均具有显著的抗菌作用,然而,光叶乌口树提取物对革兰氏阳性菌表现出最强的活性(最低抑菌浓度范围为62.5至125微克/毫升),而大果美登木提取物的抗菌谱最广,它能抑制所有测试菌株,最低抑菌浓度范围为125至250微克/毫升。

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