Isbell David C, Meyer Craig H, Rogers Walter J, Epstein Frederick H, DiMaria Joseph M, Harthun Nancy L, Wang Hongkun, Kramer Christopher M
Department of Medicine, University of Virginia Health System, Charlottesville, Virginia 22908, USA.
J Cardiovasc Magn Reson. 2007;9(1):71-6. doi: 10.1080/10976640600843330.
A high resolution, noninvasive approach to quantify atherosclerotic plaque in the peripheral vasculature could have significant clinical and research utility. Seventeen patients with peripheral arterial disease (PAD) were studied in a 1.5T CMR scanner. Atherosclerotic plaque volume in the superficial femoral artery was measured and interobserver, intraobserver, and test-retest variability determined. Nineteen vessels were studied with mean acquisition time of 13.1 minutes per vessel. Mean plaque volume was 7.27 +/- 3.73 cm3. Intra-observer intraclass correlation was R = 0.997, inter-observer was R = 0.987, and test-retest reproducibility was R = 0.996. Thus, high resolution measurement of plaque volume in PAD is reliable and reproducible.
一种用于量化外周血管系统中动脉粥样硬化斑块的高分辨率、非侵入性方法可能具有重大的临床和研究价值。在一台1.5T的心脏磁共振成像（CMR）扫描仪中对17名外周动脉疾病（PAD）患者进行了研究。测量了股浅动脉中动脉粥样硬化斑块的体积，并确定了观察者间、观察者内以及重测的变异性。对19条血管进行了研究，每条血管的平均采集时间为13.1分钟。平均斑块体积为7.27±3.73立方厘米。观察者内组内相关系数R = 0.997，观察者间为R = 0.987，重测再现性为R = 0.996。因此，对PAD中斑块体积进行高分辨率测量是可靠且可重复的。
