Shinal René M, Fillingim Roger B
Department of Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, P.O. Box 103628 Gainesville, FL 32610-3628, USA.
Dent Clin North Am. 2007 Jan;51(1):1-18, v. doi: 10.1016/j.cden.2006.09.004.
Chronic orofacial pain is a prevalent problem that encompasses numerous disorders with diverse causes and presenting symptoms. Compared with men, women of reproductive age seek treatment for orofacial pain conditions, as well as other chronic pain disorders more frequently. Important issues have been raised regarding gender and sex differences in genetic, neurophysiologic, and psychosocial aspects of pain sensitivity and analgesia. Efforts to improve our understanding of qualitative sex differences in pain modulation signify a promising step toward developing more tailored approaches to pain management.
慢性口面部疼痛是一个普遍存在的问题,它涵盖了众多病因和症状各异的疾病。与男性相比,育龄期女性更频繁地寻求口面部疼痛以及其他慢性疼痛疾病的治疗。关于疼痛敏感性和镇痛在遗传、神经生理及社会心理方面的性别差异,已经引发了重要问题。努力增进我们对疼痛调节中性别差异性质的理解,标志着朝着开发更具针对性的疼痛管理方法迈出了有希望的一步。