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首次出现精神病症状者的躯体疾病及生活方式风险因素。

Physical illness and lifestyle risk factors in people with their first presentation of psychosis.

作者信息

Samele Chiara, Patel Maxine, Boydell Jane, Leese Morven, Wessely Simon, Murray Robin

机构信息

Sainsbury Centre for Mental Health, 34-138 Borough High Street, London, SE1 1LB, UK.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2007 Feb;42(2):117-24. doi: 10.1007/s00127-006-0135-2. Epub 2006 Nov 23.

Abstract

BACKGROUND

There is an increased prevalence of physical illness and poor lifestyle in patients with chronic schizophrenia. It is unclear whether these are present at the onset of psychosis or develop over the course of illness. We aimed to establish whether patients experiencing their first episode of psychosis have worse physical health and lifestyle than community controls without psychosis.

METHOD

Eighty-nine patients with new onset illness were compared to age and sex matched controls for self-reported physical illness and cardiovascular and respiratory risk factors.

RESULTS

Patients reported more physical health complaints, mainly respiratory, compared with age and gender matched controls (odds ratio 2.85, 95% confidence interval 1.2-6.7). Patients were more likely to be cigarette smokers (1.82, 95% CI 1.0-3.3) and eat a fast food diet (1.04, 95% CI 1.0-1.1), but these differences were accounted for by patients' unemployment status.

CONCLUSIONS

Some risk factors for physical health problems are present at the onset of psychosis, but these may be explained by unemployment.

摘要

背景

慢性精神分裂症患者身体疾病患病率增加且生活方式不良。目前尚不清楚这些情况是在精神病发作时就已存在,还是在疾病过程中发展而来。我们旨在确定首次发作精神病的患者是否比无精神病的社区对照者身体健康状况更差且生活方式更不健康。

方法

将89例新发疾病患者与年龄和性别匹配的对照者进行比较,以了解自我报告的身体疾病以及心血管和呼吸风险因素。

结果

与年龄和性别匹配的对照者相比,患者报告了更多的身体健康问题,主要是呼吸系统问题(优势比2.85,95%置信区间1.2 - 6.7)。患者吸烟的可能性更大(1.82,95%置信区间1.0 - 3.3),且更常食用快餐(1.04,95%置信区间1.0 - 1.1),但这些差异可由患者的失业状况来解释。

结论

身体健康问题的一些风险因素在精神病发作时就已存在,但这些可能由失业来解释。

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