肥厚型心肌病中累积运动诱发的左心室收缩和舒张功能障碍。
Cumulative exercise-induced left ventricular systolic and diastolic dysfunction in hypertrophic cardiomyopathy.
作者信息
Pelliccia Francesco, Cianfrocca Cinzia, Pristipino Christian, Pasceri Vincenzo, Auriti Antonio, Richichi Giuseppe, Mangieri Enrico, Gaudio Carlo
出版信息
Int J Cardiol. 2007 Oct 31;122(1):76-8. doi: 10.1016/j.ijcard.2006.11.030. Epub 2006 Dec 29.
The phenomenon of cumulative exercise-induced left ventricular function impairment was studied in 40 patients with non-obstructive hypertrophic cardiomyopathy with resting normal left ventricular function and no increase in ejection fraction on exercise. All patients underwent two symptom-limited exercise tests one-hour apart. Cumulative myocardial dysfunction was seen in 13 patients (group I) but not in the remaining 27 patients (group II). During follow-up, group I showed more commonly than group II a deterioration in symptoms (67% vs 22%, P=0.025) and left ventricular function (50% vs 9%, P=0.019). In conclusion, cumulative exercise-induced myocardial dysfunction can occur in hypertrophic cardiomyopathy and may be associated with clinical deterioration and worse outcome.
在40例静息时左心室功能正常且运动时射血分数无增加的非梗阻性肥厚型心肌病患者中，研究了累积运动诱发的左心室功能损害现象。所有患者均相隔1小时进行了两次症状限制性运动试验。13例患者（I组）出现了累积心肌功能障碍，其余27例患者（II组）未出现。在随访期间，I组比II组更常见症状恶化（67%对22%，P=0.025）和左心室功能恶化（50%对9%，P=0.019）。总之，累积运动诱发的心肌功能障碍可发生于肥厚型心肌病，且可能与临床恶化及更差的预后相关。
Zotero 插件