Davis Scott, Mirick Dana K
Program In Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA.
Epidemiology. 2007 Mar;18(2):266-9. doi: 10.1097/01.ede.0000253934.58618.98.
Exposure to 60-Hz magnetic fields may increase breast cancer risk by suppressing the nocturnal production of melatonin. The use of medications associated with reduced melatonin levels could modify this relationship.
We recontacted participants in a population-based case-control study of residential magnetic field exposure and breast cancer risk and interviewed them regarding medication use during the 10 years before diagnosis. Cases were diagnosed between November 1992 and March 1995, and magnetic field levels were measured in the home at diagnosis. We obtained medication use information by telephone interview from 558 cases and 588 controls.
Breast cancer risk was not associated with exposure to residential magnetic fields, regardless of medication use.
These results support previous findings that magnetic field exposure does not increase breast cancer risk.
暴露于60赫兹的磁场可能通过抑制褪黑素的夜间分泌而增加患乳腺癌的风险。使用与褪黑素水平降低相关的药物可能会改变这种关系。
我们再次联系了一项基于人群的住宅磁场暴露与乳腺癌风险病例对照研究的参与者，并就其在诊断前10年的用药情况进行了访谈。病例在1992年11月至1995年3月期间被诊断，诊断时在家中测量磁场水平。我们通过电话访谈从558例病例和588例对照中获取用药信息。
无论用药情况如何，乳腺癌风险与住宅磁场暴露均无关联。
这些结果支持了先前的研究发现，即磁场暴露不会增加患乳腺癌的风险。
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