Jung E M, Kubale R, Clevert D-A, Weskott H-P, Prantl L, Herold T, Renz M, Rupp N, Tacke J
Institute of Diagnostic, Interventional Radiology and Neuroradiology, Klinikum Passau, Innstrasse 76, D-94032 Passau, Germany.
Clin Hemorheol Microcirc. 2007;36(1):35-46.
To investigate the extent to which B-flow and B-flow with 3D postprocessing and speckle reduction imaging (SRI) have advantages in appraising the morphology of a high-grade stenosis of the internal carotid artery (ICA) for preinterventional planning and for postinterventional ultrasonographic follow-up.
MATERIALS/METHODS: A comparative appraisal of flow with CCDS, power Doppler, B-flow and 3D B-Flow with SRI were carried out prospectively in 50 patients with >70% stenosis according to NASCET criteria in contrast medium-enhanced MRA before and after the intervention. After stenting of the internal carotid artery (ICA), i.a. digital substraction angiography (DSA) served as an additional reference method.
In >70% ICA stenosis, simultaneous imaging of the pre-stenotic, intra-stenotic and post-stenotic flow was attained with B-flow in 45/90 cases (90%), with power Doppler in 39/50 cases (78%) and with CCDS in only 31/50 cases (62%). After intervention, a complete detection of flow without overwriting or blooming artifacts was achieved in all 50 patients only by B-flow. The intrastenotic flow (p<0.05) could be better demarcated against the lumen and the vessel wall before the intervention, whereas the flow within the stent could be very much better appraised after the intervention (p<0.01) using 3D postprocessing of B-flow with additional SRI. Re-stenoses with hypoechoic vascular wall changes (3/50 patients) were detected at an early stage using B-flow.
B-flow technique with SRI and 3D postprocessing can facilitate the intrastenotic detection of flow in >70% ICA stenosis with fewer flow artifacts. After stenting, the perfused vascular lumen shows less flow artifacts compared with CCDS and power Doppler. In order to elucidate hemodynamic changes, additional Doppler examinations are still necessary.
探讨B-flow、具备三维后处理及斑点减少成像(SRI)的B-flow在评估颈内动脉(ICA)重度狭窄形态以用于介入治疗前规划及介入治疗后超声随访方面的优势程度。
材料/方法:根据NASCET标准,对50例狭窄程度>70%的患者在介入前后的对比剂增强磁共振血管造影(MRA)中,前瞻性地进行了彩色编码双功能超声(CCDS)、能量多普勒、B-flow以及具备SRI的三维B-flow的血流对比评估。在颈内动脉(ICA)支架置入术后,数字减影血管造影(DSA)作为额外的参考方法。
在ICA狭窄程度>70%时,B-flow在45/90例(90%)中实现了狭窄前、狭窄内及狭窄后血流的同步成像,能量多普勒在39/50例(78%)中实现,而CCDS仅在31/50例(62%)中实现。介入后,仅B-flow在所有50例患者中都实现了无重叠或伪像的血流完全检测。使用具备额外SRI的B-flow三维后处理,介入前狭窄内血流与管腔及血管壁的分界更清晰(p<0.05),而介入后支架内血流的评估效果要好得多(p<0.01)。使用B-flow在早期检测到了伴有低回声血管壁改变的再狭窄(3/50例患者)。
具备SRI及三维后处理的B-flow技术能够以较少的血流伪像促进对>70%的ICA狭窄内血流的检测。支架置入后,与CCDS和能量多普勒相比,灌注血管腔的血流伪像更少。为了阐明血流动力学变化,仍需要进行额外的多普勒检查。