Malik M, Camm A J
Department of Cardiological Sciences, St. George's Hospital Medical School, London, England.
Pacing Clin Electrophysiol. 1991 Oct;14(10):1492-502. doi: 10.1111/j.1540-8159.1991.tb04071.x.
This article is the first of three articles that review mathematical and computer models of the heart and describe their construction, development, research potential, and clinical utility. This article explains the methodological principles of mathematical and computer simulation of biomedical systems. The strategies of model construction, testing, and application are presented; the advantages and limitations of computer simulation studies are explained, and the basic value of computer simulation for cardiological research and practice is discussed.
本文是三篇系列文章中的第一篇，这些文章回顾了心脏的数学和计算机模型，并描述了它们的构建、发展、研究潜力和临床应用。本文解释了生物医学系统数学和计算机模拟的方法学原理。介绍了模型构建、测试和应用的策略；解释了计算机模拟研究的优点和局限性，并讨论了计算机模拟在心脏病学研究和实践中的基本价值。
