Pagano F, Zattoni F, Vianello F, Piazza R, Capitanio G
Institute of Urology, University of Padua, Italy.
Eur Urol. 1991;20 Suppl 1:31-5. doi: 10.1159/000471743.
No definite relationship can be demonstrated between benign prostatic hyperplasia (BPH) and prostatic cancer on the basis of various anatomic and morphologic features. However, interesting recent observations suggest a link between BPH and prostate cancer. Clinically, the simultaneous presence of benign and malignant disease is observed quite often, and this coexistence is bound to increase with the age of patients. Possible intermediate forms between BPH and early cancer have been investigated. Two premalignant lesions have been identified: atypical adenomatous hyperplasia and prostatic intraepithelial neoplasia.
基于各种解剖学和形态学特征，无法证实良性前列腺增生（BPH）与前列腺癌之间存在明确关系。然而，近期有趣的观察结果提示BPH与前列腺癌之间存在联系。临床上，良性和恶性疾病同时存在的情况很常见，而且这种共存情况必然会随着患者年龄的增长而增加。人们已经对BPH与早期癌症之间可能的中间形式进行了研究。已确定两种癌前病变：非典型腺瘤样增生和前列腺上皮内瘤变。
