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贝尔维尔德特管分流术中的腔内压力反应:改良技术比较

Intraluminal pressure response in Baerveldt tube shunts: a comparison of modification techniques.

作者信息

Gilbert David D, Bond Brent

机构信息

Wake Forest University Eye Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1033, USA.

出版信息

J Glaucoma. 2007 Jan;16(1):62-7. doi: 10.1097/IJG.0b013e31802b3944.

Abstract

PURPOSE

To design an apparatus for in vitro quantification of effects of modifications to nonvalved tube shunts, and to compare the effects of these modifications done to prevent early postoperative hypotony.

MATERIALS AND METHODS

A testing apparatus was designed and constructed to measure intraluminal pressure (ILP) during constant infusion of balanced salt solution at 2 microL/min through Baerveldt tube shunts mounted on cadaver eyes. Three different modifications were performed and 3 shunts were used for each modification. The modifications were partial tube occlusion with a 3-0 Supramid suture, tube perforation with a 27-gauge needle on an occluded tube, and a 1.2 mm longitudinal venting slit on an occluded tube.

RESULTS

The final steady state ILP for the 3-0 Supramid partially occluded tube ranged between 1.6 and 2.8 mm Hg over 3 trials with an average final steady state ILP of 2.0 mm Hg. The 27-gauge needle perforation produced ILPs of 4.6 to 8.2 mm Hg over 3 trials with an average final steady state pressure of 5.9 mm Hg. The 1.2 mm longitudinal venting slit produced an ILP range of 12.6 to 17.3 mm Hg over 3 trials with an average final steady state ILP of 14.8 mm Hg. The differences in final steady state ILP between the 3 modification techniques were statistically significant (P=0.00036).

CONCLUSIONS

The 3-0 Supramid occlusion and the 27-gauge perforation techniques produced hypotony, whereas the 1.2 mm longitudinal venting slit produced acceptable pressures in vitro.

摘要

目的

设计一种用于体外定量评估非瓣膜性管分流术改良效果的装置,并比较这些改良措施预防术后早期低眼压的效果。

材料与方法

设计并构建了一种测试装置,用于在以2微升/分钟的速度通过安装在尸体眼睛上的Baerveldt管分流器持续输注平衡盐溶液期间测量管腔内压力(ILP)。进行了三种不同的改良,每种改良使用3个分流器。改良措施分别为用3-0 Supramid缝线部分阻塞管腔、用27号针头在阻塞管上穿孔以及在阻塞管上设置1.2毫米的纵向排气狭缝。

结果

在3次试验中,3-0 Supramid部分阻塞管的最终稳态ILP在1.6至2.8毫米汞柱之间,平均最终稳态ILP为2.0毫米汞柱。27号针头穿孔在3次试验中产生的ILP为4.6至8.2毫米汞柱,平均最终稳态压力为5.9毫米汞柱。1.2毫米纵向排气狭缝在3次试验中产生的ILP范围为12.6至17.3毫米汞柱,平均最终稳态ILP为14.8毫米汞柱。三种改良技术在最终稳态ILP上的差异具有统计学意义(P = 0.00036)。

结论

3-0 Supramid阻塞和27号穿孔技术导致低眼压,而1.2毫米纵向排气狭缝在体外产生了可接受的压力。

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