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中暑和体力衰竭是被低估的急性肝衰竭病因吗?

Are heat stroke and physical exhaustion underestimated causes of acute hepatic failure?

作者信息

Weigand Kilian, Riediger Carina, Stremmel Wolfgang, Flechtenmacher Christa, Encke Jens

机构信息

Department of Gastroenterology and Hepatology, Medicine IV, University of Heidelberg, 69120 Heidelberg, Germany.

出版信息

World J Gastroenterol. 2007 Jan 14;13(2):306-9. doi: 10.3748/wjg.v13.i2.306.

Abstract

While cardiopulmonary symptoms are common in patients undergoing classical or, due to physical exercise, exertional heat stroke, the failure of other organs is a rarely described phenomenon. Here we present two cases of acute hepatic failure, one due to classic heat shock, while the other occurred while the patient was doing a marathon-type running. Both cases presented with very high transaminases and significantly elevated international normalized ratio (INR). No other causes for liver failure could be identified but physical exhaustion and hyperthermia.

摘要

虽然心肺症状在接受传统治疗的患者中很常见,或者由于体育锻炼而发生劳力性热射病的患者中也很常见,但其他器官衰竭是一种很少被描述的现象。在此,我们报告两例急性肝衰竭病例,一例是由于经典热休克,另一例发生在患者进行马拉松式跑步时。两例患者均出现转氨酶极高和国际标准化比值(INR)显著升高的情况。除了身体疲惫和体温过高外,未发现其他导致肝衰竭的原因。

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