Miron Dan, Daas Ahmed, Sakran Waheeb, Lumelsky Dimitry, Koren Ariel, Horovitz Yoseph
Pediatric Department A, HaEmek Medical Center, Afula, Israel.
Arch Dis Child. 2007 Jun;92(6):502-4. doi: 10.1136/adc.2006.108662. Epub 2007 Jan 16.
Guidelines recommend obtaining a renal ultrasonogram (RUS) for young children after a first urinary tract infection (UTI).
The aim of the current study was to assess the concordance of prenatal and post-UTI RUS findings in children with a first simple UTI.
This was a prospective study and included all children aged 5 years or younger who were hospitalised with a first simple UTI (determined as clinical response and normalisation of temperature within 48 h on initiation of antibacterial therapy with no complications). Data were collected from each child regarding the results of prenatal and post-UTI RUS.
Overall, 250 children were included in the study and the results of late-pregnancy and post-UTI RUS were available for 84% (n = 209). Complete concordance between the two RUS was demonstrated in 96% (n = 201). The predictive value of normal antenatal to normal post-UTI RUS was 96% (95% CI: 93% to 99%). These results include four children with mild transient pelvic dilatation. In eight children in whom renal anomalies were demonstrated only in post-UTI RUS, the influence of these anomalies on the children's management was negligible.
Prenatal-RUS have been performed in most children <5 years old hospitalised with a first simple UTI. Concordance with post-infection tests is very high. Findings which appear only in post-infectious RUS usually have negligible effects on children's management. Thus, in such children with normal antenatal RUS omitting post-UTI RUS could be considered.
指南建议对首次发生尿路感染(UTI)的幼儿进行肾脏超声检查(RUS)。
本研究旨在评估首次单纯性UTI患儿产前和UTI后RUS检查结果的一致性。
这是一项前瞻性研究,纳入了所有5岁及以下因首次单纯性UTI住院的儿童(定义为抗菌治疗开始后48小时内临床症状缓解且体温恢复正常,无并发症)。收集每个儿童产前和UTI后RUS检查的结果。
总体而言,250名儿童纳入本研究,其中84%(n = 209)有孕晚期和UTI后RUS检查结果。两次RUS检查结果完全一致的比例为96%(n = 201)。产前RUS正常对UTI后RUS正常的预测价值为96%(95%CI:93%至99%)。这些结果包括4名轻度短暂性肾盂扩张的儿童。在8名仅在UTI后RUS检查中发现肾脏异常的儿童中,这些异常对儿童治疗的影响可忽略不计。
大多数5岁以下因首次单纯性UTI住院的儿童已进行产前RUS检查。与感染后检查的一致性非常高。仅在感染后RUS检查中出现的结果通常对儿童治疗影响可忽略不计。因此,对于产前RUS正常的此类儿童,可考虑省略UTI后RUS检查。