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[依诺沙星治疗前列腺腺瘤患者无症状菌尿症]

[Enoxacin in the treatment of asymptomatic bacteriuria in patients with prostatic adenoma].

作者信息

Cortecchia W, Beghelli R, Frigola M, Soli M, Lo Cigno M, Emili E, D'Amato G, Dal Pra M L

机构信息

Clinica Urologica Osp. Sant'Orsola-Bologna.

出版信息

Arch Ital Urol Nefrol Androl. 1991 Sep;63(3):327-30.

PMID:1723219
Abstract

Fifty patients suffering from prostatic adenoma with asymptomatic bacteriuria, were admitted to an open non comparative trial. Enoxacin was administered at the daily dosage of 300 mg every 12 hours for 10 days. Three cycles of treatment were performed during three consecutive months. Treatment efficacy was established by assessing patient symptoms related to the infection such as pollakiuria , nocturia, decreased flow rate, stranguria, daily temperature. Cultural tests were also performed. All observations were collected at baseline and at the end of each cycle of therapy. Cure was obtained in 43 patients (87, 75%), 1 patient (2,04%) relapsed, 5 patients (10.2%) withdrew because of inefficacy of treatment and 1 patient died of heart failure. No side effects were observed. These results suggest that enoxacin may be successfully used in the treatment of asymptomatic bacteriuria.

摘要

五十名患有前列腺腺瘤并伴有无症状菌尿症的患者参加了一项开放性非对照试验。依诺沙星的给药剂量为每12小时300毫克,持续10天。在连续三个月内进行了三个疗程的治疗。通过评估与感染相关的患者症状,如尿频、夜尿、尿流率降低、尿痛、每日体温,来确定治疗效果。还进行了培养测试。所有观察数据均在基线和每个治疗周期结束时收集。43名患者(87.75%)治愈,1名患者(2.04%)复发,5名患者(10.2%)因治疗无效而退出,1名患者死于心力衰竭。未观察到副作用。这些结果表明,依诺沙星可成功用于治疗无症状菌尿症。

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