Cooper Jason G, Purcell Gretchen P
Duke University - Division of Clinical Informatics, Durham, NC, USA.
AMIA Annu Symp Proc. 2006;2006:897.
Crohn's disease is a debilitating condition that affects the entire gastrointestinal tract and often requires aggressive and invasive therapies. Several studies have suggested dietary triggers for disease activity. We have created a web-based tool to allow participants to record both daily food intake and wellness (i.e., disease-specific quality of life). We seek to determine if measurable correlations exist between these events in patients with Crohn's disease. Advanced data mining techniques are employed to find such correlations and the efficacies of chosen techniques are assessed. We tested our web-based system in a pilot study involving 7 participants, and we found that traditional statistical techniques identified diet and disease activity correlations in short-term data sets.
克罗恩病是一种使人虚弱的疾病，会影响整个胃肠道，通常需要积极且侵入性的治疗。多项研究表明饮食会引发疾病活动。我们创建了一个基于网络的工具，使参与者能够记录每日食物摄入量和健康状况（即特定疾病的生活质量）。我们试图确定在克罗恩病患者中，这些因素之间是否存在可测量的相关性。采用先进的数据挖掘技术来寻找此类相关性，并评估所选技术的有效性。我们在一项涉及7名参与者的初步研究中测试了我们基于网络的系统，发现传统统计技术在短期数据集中识别出了饮食与疾病活动之间的相关性。
