McCallum Jan M, Arekere Dhananjaya M, Green B Lee, Katz Ralph V, Rivers Brian M
Department of Health and Kinesiology, Office of Health Informatics, Center for the Study of Health Disparities, Texas A&M University, USA.
J Health Care Poor Underserved. 2006 Nov;17(4):716-33. doi: 10.1353/hpu.2006.0130.
The purpose of this review was to collect and interpret the findings of all published qualitative or quantitative research that assessed African Americans' 1) general awareness and/or specific knowledge of the U.S. Public Health Service (USPHS) Syphilis Study at Tuskegee, and 2) attitudes towards and/or willingness to participate in biomedical research. An exhaustive review of the literature produced eight articles that fit the aforementioned selection criteria. All articles that assessed both awareness and knowledge found that familiarity with the USPHS Syphilis Study at Tuskegee did not necessarily ensure accurate knowledge of it. Four studies also found that awareness of the USPHS Syphilis Study at Tuskegee did not relate to willingness to participate in biomedical research. In addition to awareness and knowledge of the USPHS Syphilis Study at Tuskegee, published studies suggest that a broad array of structural and sociocultural factors influence minorities' willingness to participate in biomedical studies.
本综述的目的是收集并解读所有已发表的定性或定量研究的结果,这些研究评估了非裔美国人:1)对美国公共卫生服务部(USPHS)塔斯基吉梅毒研究的总体认识和/或具体了解;2)对生物医学研究的态度和/或参与意愿。对文献进行详尽检索后,筛选出八篇符合上述选择标准的文章。所有评估了认识和了解情况的文章均发现,对USPHS塔斯基吉梅毒研究的熟悉程度并不一定能确保对其有准确的认知。四项研究还发现,对USPHS塔斯基吉梅毒研究的了解与参与生物医学研究的意愿并无关联。除了对USPHS塔斯基吉梅毒研究的认识和了解之外,已发表的研究表明,一系列广泛的结构和社会文化因素会影响少数群体参与生物医学研究的意愿。