质子辅助的不灵敏核交叉极化
Proton assisted insensitive nuclei cross polarization.
作者信息
Lewandowski Józef R, De Paëpe Gaël, Griffin Robert G
机构信息
Department of Chemistry and Francis Bitter Magnet Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
出版信息
J Am Chem Soc. 2007 Jan 31;129(4):728-9. doi: 10.1021/ja0650394.
Abstract
This communication presents a solid-state NMR N-C polarization transfer scheme applicable at high B and high MAS frequencies, requiring moderate r.f. powers (~50 kHz C/N) and mixing time (1–6 ms). The sequence, PAIN-CP, involves the abundant nearby protons in the heteronuclear recoupling dynamics, and provides a new tool for obtaining long distance N-C contacts. It should be of major interest for biomolecular structural studies.
摘要
本通讯介绍了一种适用于高磁场和高魔角旋转频率的固态核磁共振N-C极化转移方案，该方案需要中等射频功率（约50 kHz C/N）和混合时间（1-6毫秒）。该序列PAIN-CP在异核再耦合动力学中涉及丰富的邻近质子，并为获得长距离N-C接触提供了一种新工具。它对于生物分子结构研究应该具有重要意义。
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