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果蝇中基因产物的发育利用:母-合子过渡。

Developmental use of gene products in Drosophila: the maternal-zygotic transition.

机构信息

Department of Zoology and Genetics Program, Michigan State University, East Lansing, Michigan 48824.

出版信息

Genetics. 1984 Oct;108(2):361-75. doi: 10.1093/genetics/108.2.361.

Abstract

Recent results suggest that activity of a large fraction of the Drosophila genome is needed at multiple developmental stages. The timing of the transition from dependence on maternally stored gene products to reliance on zygotically coded products has been examined for several zygotic-lethal mutations in the z-w region of the X chromosome. The mutants differ in zygotic sensitivity to reduced maternal activity, and they have a wide range of times of lethality. Nevertheless, both temperature shift experiments and clonal analysis indicate that all of the maternal-zygotic transitions occur around the time of blastoderm formation.

摘要

最近的研究结果表明,果蝇基因组的很大一部分活性在多个发育阶段都是必需的。人们已经研究了 X 染色体 z 区的几个合子致死突变,以确定从依赖母源储存的基因产物过渡到依赖合子编码产物的时间。这些突变体在合子对母源活性降低的敏感性方面存在差异,并且它们的致死时间范围很广。然而,温度转换实验和克隆分析都表明,所有的母源-合子过渡都发生在胚胎形成时期。

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