Datta Vivekanand, Rawal Yeshwant B, Mincer Harry H, Anderson Mark K
Department of Pathology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Head Neck. 2007 Jun;29(6):605-8. doi: 10.1002/hed.20548.
Myopericytoma is a rare mesenchymal neoplasm of pericytic cells demonstrating myoid differentiation. The lesion typically arises within the subcutaneous tissue of the extremities. We report a case that, to the best of our knowledge, is the first case of myopericytoma involving the soft tissue of the oral cavity.
A 36-year-old woman had a 5-mm sessile, whitish-pink, firm tongue nodule. The patient underwent excisional biopsy, and histopathologic examination as well as immunohistochemical analysis were performed.
The differential diagnosis by histologic analysis included solitary fibrous tumor, myofibroma, glomus tumor, and myopericytoma. The results of immunohistochemical analysis, when combined with the histologic features, led to a diagnosis of myopericytoma.
Applying strict morphologic criteria and appropriately selective immunohistochemical markers will help to distinguish myopericytoma in the oral cavity.
肌周细胞瘤是一种罕见的间叶性肿瘤，由具有肌样分化的周细胞构成。该病变通常发生于四肢的皮下组织。据我们所知，我们报告了首例累及口腔软组织的肌周细胞瘤病例。
一名36岁女性舌部有一个5毫米大小的无蒂、淡粉白色、质地坚硬的结节。患者接受了切除活检，并进行了组织病理学检查和免疫组化分析。
组织学分析的鉴别诊断包括孤立性纤维瘤、肌纤维瘤、血管球瘤和肌周细胞瘤。免疫组化分析结果结合组织学特征，诊断为肌周细胞瘤。
应用严格的形态学标准和适当选择免疫组化标志物有助于鉴别口腔内的肌周细胞瘤。
