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在复合暴露后,社交隔离会立即干扰事件内学习。

Within-event learning is disrupted by social isolation immediately after compound exposure.

作者信息

Bailey Glynis K, Westbrook R Frederick

机构信息

The University of New South Wales, Australia.

出版信息

Behav Brain Res. 2007 Mar 28;178(2):313-6. doi: 10.1016/j.bbr.2006.12.017. Epub 2006 Dec 21.

DOI:10.1016/j.bbr.2006.12.017
PMID:17254643
Abstract

Exposure to banana scented salty water produced a preference for that smell in rats tested under a sodium appetite (experiment 1), and exposure to almond scented sweet water produced avoidance of that smell when rats were tested after developing an aversion to the sweet taste (experiment 2). The consolidation of this within-event learning was disrupted when exposure to the solutions were followed by social isolation. These results duplicate the disruptive effect of social isolation on context learning and raise the possibility that within-event learning like context learning may involve the hippocampal formation.

摘要

在钠食欲测试中(实验1),接触香蕉味咸水使大鼠对该气味产生偏好;而在对甜味产生厌恶后进行测试时(实验2),接触杏仁味甜水使大鼠对该气味产生回避。当接触溶液后紧接着进行社会隔离时,这种事件内学习的巩固受到干扰。这些结果重复了社会隔离对情境学习的破坏作用,并增加了像情境学习这样的事件内学习可能涉及海马结构的可能性。

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