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[乳腺恶性肿瘤的组织学分类。最新概念]

[Histological classification of malignant breast neoplasms. Recent concepts].

作者信息

Hébert H, Gentile-Fradet A

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1975;4 SUPPL 2:21-40.

PMID:172553
Abstract

The recent histological classifications of breast malignant epithelial tumours place increased emphasis on several concepts: in situ carcinoma, difference of lobular carcinoma from other forms of breast cancer and histological factors of prognosis. The authors propose to discriminate: non infiltrating duct carcinoma (intraductal carcinoma); lobular carcinoma (in situ and infiltrating); infiltrating duct carcinoma in their usual form (80 p. 100 about of all breast carcinoma); among them, histological types with a less ominous prognosis, although relatively rare, are stressed (infiltrating papillary and comedo-carcinomas, tubular carcinoma, medullary carcinoma, colloid carcinoma, cylindroma, certain metaplastic variants, Paget's disease of the nipple); some features in unusual hosts are related. They mention the criteria of the Scarff and Bloom's "grading" and its importance from the point of view of prognosis, mainly for the usual infiltrating forms. Other malignant tumours of the breast (malignant cystosarcoma phyllodes, sarcomas, mammary metastases) are more scarcely seen (I p. 100 of the mammary neoplasms): their classification is succinctly recalled.

摘要

近期乳腺恶性上皮性肿瘤的组织学分类更加强调了几个概念

原位癌、小叶癌与其他形式乳腺癌的差异以及预后的组织学因素。作者提议区分:非浸润性导管癌(导管内癌);小叶癌(原位和浸润性);常见形式的浸润性导管癌(约占所有乳腺癌的80%);其中,强调了预后相对较好但相对罕见的组织学类型(浸润性乳头状癌和粉刺癌、管状癌、髓样癌、黏液癌、圆柱瘤、某些化生变体、乳头派杰病);提及了不常见类型的一些特征。他们提到了斯卡夫和布鲁姆“分级”标准及其从预后角度的重要性,主要针对常见的浸润性类型。其他乳腺恶性肿瘤(恶性叶状囊肉瘤、肉瘤、乳腺转移瘤)较为少见(占乳腺肿瘤的1%):简要回顾了它们的分类。

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