Gol'bert Z V, Sorkin E E
Arkh Patol. 1977;39(7):81-9.
The histological characterization of mammary cancer (MC) is of leading importance for prognosis and choice of therapeutic methods (directed hormonal and chemotherapy). In this respect of interest is the morphological picture of a special form of MC, lobular cancer which is characterized by the most malignant course, marked infiltrative and less manifest destructive growth, multicentricity and multiplicity, as well as bilateral foci of lesions. It probably originates from the myoepithelium. In the national literature, no information on lobular MC is available. Little information is available on the precursor of lobular MC, lobular carcinoma in situ. This problem is insufficiently and inaccurately dealth with in the International classification of mammary gland tumors (WHO). A review of literature on lobular MC, as well as photomicrographs of its structure and that of its precursor are presented.
乳腺癌（MC）的组织学特征对于预后及治疗方法（激素治疗和化疗）的选择至关重要。在这方面，一种特殊形式的MC——小叶癌的形态学表现备受关注。小叶癌的特点是病程最为恶性，浸润性明显且破坏性生长不显著，多中心性和多发性，以及双侧病灶。它可能起源于肌上皮。在国内文献中，尚无关于小叶MC的信息。关于小叶MC的前驱病变——小叶原位癌的信息也很少。在《世界卫生组织乳腺肿瘤国际分类》中，这个问题的处理不够充分且不准确。本文呈现了关于小叶MC的文献综述及其结构和前驱病变的显微照片。
