Kouchoukos Nicholas T, Mauney Michael C, Masetti Paolo, Castner Catherine F
Division of Cardiovascular and Thoracic Surgery, Missouri Baptist Medical Center, St. Louis, Missouri, USA.
Ann Thorac Surg. 2007 Feb;83(2):S811-4; discussion S824-31. doi: 10.1016/j.athoracsur.2006.10.095.
Staged procedures for extensive aneurysmal disease of the thoracic aorta are associated with a substantial cumulative mortality for the two procedures and death in the interval between, often from aortic rupture. We have used a one-stage approach for operative repair of most, or all, of the thoracic aorta.
Sixty-nine patients were treated using a bilateral anterior thoracotomy with transverse sternotomy, hypothermic circulatory arrest, and reperfusion of the arch vessels first to minimize brain ischemia. Forty-two patients had chronic ascending aortic dissections (all but 1 had a previous operation), 24 had degenerative aneurysms, and 3 had chronic descending aortic dissections with proximal extension. The ascending aorta and aortic arch were replaced in all patients combined with resection of various lengths of descending aorta.
In-hospital mortality was 7.2% (5 patients). Morbidity included reoperation for bleeding (13%), mechanical ventilation for more than 72 hours (50%), temporary tracheostomy (13%), and temporary renal dialysis (9%). No patient sustained a stroke. There have been 9 late deaths unrelated to the aortic disease. Four patients have undergone successful reoperation on the aorta for false aneurysm in 1, endocarditis in 1, and progression of disease in 2. Survival at 5 years was 71%.
The one-stage arch-first technique is a safe and suitable alternative to the two-stage procedure for repair of extensive thoracic aortic disease.
对于广泛的胸主动脉瘤性疾病,分期手术会使这两个手术的累积死亡率大幅升高,且在间隔期常因主动脉破裂导致死亡。我们采用了一期手术方法来修复大部分或全部胸主动脉。
69例患者采用双侧前外侧开胸联合胸骨正中切开术,在低温循环停止下,先对主动脉弓血管进行再灌注以尽量减少脑缺血。42例患者患有慢性升主动脉夹层(除1例之外均曾接受过手术),24例患有退行性动脉瘤,3例患有累及近端的慢性降主动脉夹层。所有患者均行升主动脉和主动脉弓置换,并联合切除不同长度的降主动脉。
住院死亡率为7.2%(5例患者)。并发症包括因出血再次手术(13%)、机械通气超过72小时(50%)、临时气管切开(13%)以及临时肾透析(9%)。无一例患者发生卒中。有9例晚期死亡与主动脉疾病无关。4例患者因假性动脉瘤(1例)、心内膜炎(1例)以及疾病进展(2例)成功接受了主动脉再次手术。5年生存率为71%。
对于广泛的胸主动脉疾病修复,一期先处理主动脉弓技术是一种安全且合适的替代分期手术的方法。