Yonemori K, Tateishi U, Tsuta K, Yonemori Y, Uno H, Asamura H, Kusumoto M
Department of Diagnostic Radiology, National Cancer Centre Hospital, Tokyo, Japan.
Int J Tuberc Lung Dis. 2007 Feb;11(2):215-21.
To analyse the clinical features and high resolution computed tomography (HRCT) findings of solitary pulmonary granulomas caused by the Mycobacterium avium-intracellulare (MAI) complex.
We retrospectively analysed a series of 73 consecutive patients with solitary pulmonary granuloma and negative sputum smear and culture results, in whom the diagnosis was established by histological examination of specimens obtained by partial pulmonary resection or lobectomy. We compared the clinical features and HRCT findings of the solitary pulmonary granulomas definitively diagnosed to be caused by the MAI complex with those of granulomas of other causes by univariate and multivariate analyses.
In this study series of 24 patients with solitary pulmonary granuloma, the aetiological agent was established as being the MAI complex. According to the results of the multivariate analysis, 'female sex', 'pleural indentation' and 'lobulation' on the HRCT images were significantly associated with solitary pulmonary granuloma caused by the MAI complex.
This study demonstrated several characteristics of solitary pulmonary granulomas caused by the MAI complex, and suggested that it might be a subtype of pulmonary MAI complex infection without the typical radiographic features of the infection.
分析鸟分枝杆菌-胞内分枝杆菌（MAI）复合体所致孤立性肺肉芽肿的临床特征及高分辨率计算机断层扫描（HRCT）表现。
我们回顾性分析了连续73例孤立性肺肉芽肿患者，这些患者痰涂片和培养结果均为阴性，通过部分肺切除或肺叶切除获取的标本组织学检查确诊。我们通过单因素和多因素分析，比较了最终诊断为由MAI复合体引起的孤立性肺肉芽肿与其他病因所致肉芽肿的临床特征和HRCT表现。
在这个包含24例孤立性肺肉芽肿患者的研究系列中，病原体被确定为MAI复合体。根据多因素分析结果，HRCT图像上的“女性”“胸膜凹陷”和“分叶”与MAI复合体所致孤立性肺肉芽肿显著相关。
本研究展示了MAI复合体所致孤立性肺肉芽肿的几个特征，并表明其可能是肺MAI复合体感染的一种亚型，无该感染典型的影像学特征。
