Hsu Charles S, Hentz Vincent R, Yao Jeffrey
Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, Palo Alto, CA 94305, USA.
Lancet Oncol. 2007 Feb;8(2):157-66. doi: 10.1016/S1470-2045(07)70035-9.
Hand tumours of soft-tissue and bony origin are frequently encountered, and clinicians must be able to distinguish typical benign entities from life-threatening or limb-threatening malignant diseases. In this Review, we present a diagnostic approach to hand tumours and describe selected cancers and their treatments. Soft-tissue tumours include ganglion cysts, giant-cell cancers and fibromas of the tendon sheath, epidermal inclusion cysts, lipomas, vascular lesions, peripheral-nerve tumours, skin cancers, and soft-tissue sarcomas. Bony tumours encompass enchondromas, aneurysmal bone cysts, osteoid osteomas, giant-cell lesions of bone, bone sarcomas, and metastases. We look at rates of recurrence and 5-year survival, and recommendations for adjunct chemotherapy and radiotherapy for malignant lesions.
软组织和骨源性手部肿瘤很常见,临床医生必须能够区分典型的良性病变与危及生命或肢体的恶性疾病。在本综述中,我们提出了一种手部肿瘤的诊断方法,并描述了选定的癌症及其治疗方法。软组织肿瘤包括腱鞘囊肿、巨细胞瘤和腱鞘纤维瘤、表皮样囊肿、脂肪瘤、血管病变、周围神经肿瘤、皮肤癌和软组织肉瘤。骨肿瘤包括内生软骨瘤、动脉瘤样骨囊肿、骨样骨瘤、骨巨细胞瘤、骨肉瘤和转移瘤。我们研究了复发率和5年生存率,以及针对恶性病变的辅助化疗和放疗建议。