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上肢良性神经肿瘤:基于登记的症状和手术结果研究。

Benign nerve tumours in the upper limb: a registry-based study of symptoms and surgical outcome.

机构信息

Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.

Department of Orthopaedics, Helsingborg Hospital, Helsingborg, Sweden.

出版信息

Sci Rep. 2023 Jul 17;13(1):11500. doi: 10.1038/s41598-023-38184-9.

Abstract

Surgery for benign nerve tumours is performed for pathoanatomical diagnosis and symptomatic relief, but might cause residual problems. We aimed to assess patient-reported symptoms and disability before and after surgery at a national level. In total, 206 cases surgically treated for a benign peripheral nerve tumour 2010-2019 registered in the Swedish Quality Registry for Hand Surgery (HAKIR; response rates 22-34%) were analysed. Surgery reduced overall disability in the affected limb (QuickDASH 18/100 [IQR 5-36] preoperatively and 5/100 [IQR 0-22] 12 months postoperatively), improved ability to perform daily activities (HQ-8; 11/100 [IQR 0-50] preoperatively and 0/100 [IQR 0-20] 12 months postoperatively) and decreased three evaluated pain modalities: pain at rest (HQ-8; 20/100 [IQR 0-40] preoperatively and 0/100 [IQR 0-10] 12 months postoperatively), pain on motion without load (HQ-8; 20/100 [IQR 0-40] preoperatively and 0/100 [IQR 0-10] 12 months postoperatively), and pain on load (HQ-8; 24/100 [IQR 1-69] preoperatively and 1/100 [IQR 0-30] 12 months postoperatively). Cold sensitivity was a minor problem both before and after surgery (HQ-8; 0/100 [IQR 0-30] preoperatively and 1/100 [IQR 0-40] 12 months postoperatively). We conclude that surgery for benign peripheral nerve tumours provides good symptomatic relief with low risk for residual problems.

摘要

手术治疗良性周围神经肿瘤的目的是进行病理解剖诊断和缓解症状,但可能会导致残留问题。我们旨在评估全国范围内良性周围神经肿瘤患者手术前后的报告症状和残疾情况。总共分析了 2010 年至 2019 年在瑞典手部手术质量登记处(HAKIR;应答率为 22%-34%)登记的 206 例良性周围神经肿瘤手术治疗病例。手术降低了患肢的整体残疾程度(QuickDASH 18/100[5-36 的 IQR]术前和 12 个月时的 5/100[0-22 的 IQR]),提高了日常活动能力(HQ-8;11/100[0-50 的 IQR]术前和 12 个月时的 0/100[0-20 的 IQR]),并降低了三种评估疼痛模式:静息时疼痛(HQ-8;20/100[0-40 的 IQR]术前和 12 个月时的 0/100[0-10 的 IQR]),无负荷运动时疼痛(HQ-8;20/100[0-40 的 IQR]术前和 12 个月时的 0/100[0-10 的 IQR]),和负荷时疼痛(HQ-8;24/100[1-69 的 IQR]术前和 12 个月时的 1/100[0-30 的 IQR])。手术前后冷敏均为小问题(HQ-8;0/100[0-30 的 IQR]术前和 12 个月时的 1/100[0-40 的 IQR])。我们的结论是,手术治疗良性周围神经肿瘤可提供良好的症状缓解,且残留问题风险低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a801/10352292/69b97678d18e/41598_2023_38184_Fig1_HTML.jpg

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