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睡眠呼吸障碍与纤维肌痛综合征并存。

Sleep disordered breathing concomitant with fibromyalgia syndrome.

作者信息

Germanowicz Dienaro, Lumertz Magali Santos, Martinez Denis, Margarites Ane Freitas

机构信息

Federação de Estabelecimento de Ensino Superior, Novo Hamburgo, Rio Grande do Sul, Brazil.

出版信息

J Bras Pneumol. 2006 Jul-Aug;32(4):333-8.

Abstract

OBJECTIVE

To identify fibromyalgia syndrome in patients with sleep disordered breathing.

METHOD

We studied 50 patients seeking treatment at a sleep disorder clinic for snoring, apnea and excessive daytime sleepiness. Sleep disordered breathing was diagnosed through the use of polysomnography. To diagnose fibromyalgia syndrome, patients were evaluated in accordance with the criteria established by the American College of Rheumatology.

RESULTS

Of the 50 patients, 32 were male. The mean (+/- standard deviation) age of the group was 50 +/- 12 years. The mean body mass index was 29.7 +/- 5.6 kg/m(2). The mean apnea-hypopnea index was 36 +/- 29 attacks of apnea or hypopnea per hour of sleep. Of the 18 women and 32 men evaluated, 9 and 2, respectively, met the American College of Rheumatology criteria for fibromyalgia syndrome.

CONCLUSION

Considering the fact that the prevalence of fibromyalgia syndrome in the general population is 0.5% for men and 3.4% for women, the more than ten-fold higher proportion of fibromyalgia cases seen in this sample supports the hypothesis that there is an association between sleep disordered breathing and fibromyalgia syndrome.

摘要

目的

识别睡眠呼吸障碍患者中的纤维肌痛综合征。

方法

我们研究了50名在睡眠障碍诊所因打鼾、呼吸暂停和日间过度嗜睡而寻求治疗的患者。通过多导睡眠图诊断睡眠呼吸障碍。为诊断纤维肌痛综合征,根据美国风湿病学会制定的标准对患者进行评估。

结果

50名患者中,32名男性。该组的平均(±标准差)年龄为50±12岁。平均体重指数为29.7±5.6kg/m²。平均呼吸暂停低通气指数为每小时睡眠中36±29次呼吸暂停或低通气发作。在评估的18名女性和32名男性中,分别有9名和2名符合美国风湿病学会纤维肌痛综合征标准。

结论

考虑到一般人群中纤维肌痛综合征的患病率男性为0.5%,女性为3.4%,该样本中纤维肌痛病例比例高出十多倍,支持睡眠呼吸障碍与纤维肌痛综合征之间存在关联的假设。

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