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慢性阻塞性肺疾病及相关营养并发症的营养治疗

Nutrition therapy for chronic obstructive pulmonary disease and related nutritional complications.

作者信息

Fernandes Amanda Carla, Bezerra Olívia Maria de Paula Alves

机构信息

Universidade Federal de Ouro Preto, Ouro Preto, MG, Brasil.

出版信息

J Bras Pneumol. 2006 Sep-Oct;32(5):461-71.

PMID:17268751
Abstract

Chronic obstructive pulmonary disease is characterized by progressive and partially reversible airway obstruction. The innumerable complications that occur during the progression of the disease can affect the nutritional state of patients suffering from this illness. The objective of this study was to present a brief review of the literature regarding the nutrition therapy used in the treatment of chronic obstructive pulmonary disease. To that end, we performed a bibliographic search for related articles published within the last 18 years and indexed for the Literatura Latinoamericana y del Caribe en Ciencias de la Salud (LILACS, Latin American and Caribbean Health Sciences Literature) and Medline databases. Malnutrition is associated with a poor prognosis for patients with chronic obstructive pulmonary disease, since it predisposes such patients to infections, as well as reducing respiratory muscle force, exercise tolerance and quality of life. Despite the fact that such malnutrition is extremely common in chronic obstructive pulmonary disease patients, it should be recognized as an independent risk factor, since it can be modified through appropriate and efficacious diet therapy and monitoring. For patients with chronic obstructive pulmonary disease, nutrition therapy is initiated after the evaluation of the nutritional state of the patient, which identifies nutritional risk, thereby allowing the proper level of treatment to be established. In this evaluation, anthropometric and biochemical markers, as well as indicators of dietary consumption and body composition, should be used. The prescribed diet should contain appropriate proportions of macronutrients, micronutrients and immunonutrients in order to regain or maintain the proper nutritional state and to avoid complications. The physical characteristics of the diet should be tailored to the individual needs and tolerances of each patient. In the treatment of patients with chronic obstructive pulmonary disease, individualized nutrition therapy is extremely important and has been shown to be fundamental to improving quality of life.

摘要

慢性阻塞性肺疾病的特征是进行性且部分可逆的气道阻塞。在疾病进展过程中出现的无数并发症会影响患有这种疾病的患者的营养状况。本研究的目的是简要回顾有关用于治疗慢性阻塞性肺疾病的营养疗法的文献。为此,我们对过去18年内发表的相关文章进行了文献检索,并在拉丁美洲和加勒比卫生科学文献数据库(LILACS)和医学数据库中进行了索引。营养不良与慢性阻塞性肺疾病患者的不良预后相关,因为它使这些患者易受感染,还会降低呼吸肌力、运动耐力和生活质量。尽管这种营养不良在慢性阻塞性肺疾病患者中极为常见,但它应被视为一个独立的危险因素,因为可以通过适当有效的饮食治疗和监测来加以改善。对于慢性阻塞性肺疾病患者,在评估患者的营养状况后开始营养治疗,该评估可识别营养风险,从而确定适当的治疗水平。在该评估中,应使用人体测量和生化指标以及饮食摄入和身体成分指标。规定的饮食应包含适当比例的宏量营养素、微量营养素和免疫营养素,以恢复或维持适当的营养状况并避免并发症。饮食的物理特性应根据每个患者的个体需求和耐受性进行调整。在治疗慢性阻塞性肺疾病患者时,个性化营养治疗极为重要,并且已被证明是改善生活质量的基础。

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引用本文的文献

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The Role of Nutrition and Nutritional Supplements in the Prevention and Treatment of Malnutrition in Chronic Obstructive Pulmonary Disease: Current Approaches in Nutrition Therapy.营养与营养补充剂在慢性阻塞性肺疾病营养不良防治中的作用:营养治疗的当前方法
Curr Nutr Rep. 2025 Jan 25;14(1):21. doi: 10.1007/s13668-025-00613-8.
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Effects of nutrients on immunomodulation in patients with severe COVID-19: Current knowledge.营养物质对重症新型冠状病毒肺炎患者免疫调节的影响:当前认知
World J Crit Care Med. 2022 Jul 9;11(4):201-218. doi: 10.5492/wjccm.v11.i4.201.
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Assessment of energy intake in women with chronic obstructive pulmonary disease: a doubly labeled water method study.
评估慢性阻塞性肺疾病女性的能量摄入:双标记水法研究。
J Nutr Health Aging. 2015 May;19(5):518-24. doi: 10.1007/s12603-014-0575-4.
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Validation of SenseWear Armband and ActiHeart monitors for assessments of daily energy expenditure in free-living women with chronic obstructive pulmonary disease.验证SenseWear臂带和ActiHeart监测仪在评估慢性阻塞性肺疾病自由生活女性日常能量消耗中的应用。
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Eur Respir Rev. 2013 Sep 1;22(129):405-13. doi: 10.1183/09059180.00002913.
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Resting energy expenditure and carbohydrate oxidation are higher in elderly patients with COPD: a case control study.静息能量消耗和碳水化合物氧化在老年 COPD 患者中更高:一项病例对照研究。
Nutr J. 2012 Jun 6;11:37. doi: 10.1186/1475-2891-11-37.