Modarres Mehdi, Sanjari Mostafa Soltan, Falavarjani Khalil Ghasemi
Department of Ophthalmology, Rasool Akram Medical Center, Tehran, Iran.
Ophthalmology. 2007 Feb;114(2):340-4. doi: 10.1016/j.ophtha.2006.07.063.
To study the results of vitrectomy and release of epipapillary vitreous adhesions for the treatment of nonarteritic anterior ischemic optic neuropathy (NAION) associated with partial posterior vitreous detachment (PVD).
Prospective noncomparative interventional case series.
A series of 16 patients with clinical picture of NAION and small discs associated with partial PVD, diagnosed clinically and confirmed by optical coherence tomography and B-scan ultrasonography.
All patients underwent standard pars plana vitrectomy with meticulous removal of epipapillary vitreous adhesions within 1 month from the onset of visual symptoms.
Best-corrected visual acuity (BCVA), mean deviation of visual fields, and color vision testing.
In 15 patients BCVA improved (93.7%), mean preoperative BCVA was 6/38 (0.82+/-0.53 logarithm of the minimum angle of resolution [logMAR]), which improved to 6/18 (0.49+/-0.37 logMAR) postoperatively at 3 months. Nine eyes (56%) had > or =3 lines of visual improvement. Visual fields improved in 4 patients and color vision improved in 1 patient.
Vitreous traction from partial PVD may have a causative role in some cases of NAION associated with small discs. In these cases, vitrectomy and removal of epipapillary vitreous may result in improvement of visual acuity.
研究玻璃体切除术及视乳头前玻璃体粘连松解术治疗与部分性玻璃体后脱离(PVD)相关的非动脉炎性前部缺血性视神经病变(NAION)的效果。
前瞻性非对照性干预病例系列。
一系列16例具有NAION临床表现且视盘小并伴有部分性PVD的患者,经临床诊断并通过光学相干断层扫描和B超检查得以确诊。
所有患者在出现视觉症状后1个月内均接受了标准的平坦部玻璃体切除术,并仔细清除视乳头前玻璃体粘连。
最佳矫正视力(BCVA)、视野平均偏差及色觉测试。
15例患者(93.7%)的BCVA得到改善,术前平均BCVA为6/38(最小分辨角对数[logMAR]为0.82±0.53),术后3个月改善至6/18(logMAR为0.49±0.37)。9只眼(56%)视力提高了≥3行。4例患者视野改善,1例患者色觉改善。
部分性PVD引起的玻璃体牵拉在一些伴有小视盘的NAION病例中可能起致病作用。在这些病例中,玻璃体切除术及视乳头前玻璃体清除术可能会提高视力。